LRG1 Protein (AA 36-347) (His tag)
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- Target See all LRG1 Proteins
- LRG1 (Leucine-Rich alpha-2 Glycoprotein 1 (LRG1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 36-347
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This LRG1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
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VTLSPKD CQVFRSDHGS SISCQPPAEI PGYLPADTVH LAVEFFNLTH LPANLLQGAS KLQELHLSSN GLESLSPEFL RPVPQLRVLD LTRNALTGLP PGLFQASATL DTLVLKENQL EVLEVSWLHG LKALGHLDLS GNRLRKLPPG LLANFTLLRT LDLGENQLET LPPDLLRGPL QLERLHLEGN KLQVLGKDLL LPQPDLRYLF LNGNKLARVA AGAFQGLRQL DMLDLSNNSL ASVPEGLWAS LGQPNWDMRD GFDISGNPWI CDQNLSDLYR WLQAQKDKMF SQNDTRCAGP EAVKGQTLLA VAKSQ - Purity
- > 95% by SDS-PAGE
- Endotoxin Level
- < 1 EU per 1ug of protein (determined by LAL method)
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- Discover our top product LRG1 Protein
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Leucine-Rich alpha-2 Glycoprotein 1 (LRG1) (AA 36-347) protein (His tag)
LRG1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Leucine-Rich alpha-2 Glycoprotein 1 (LRG1) (AA 72-383) protein (His tag)LRG1 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Leucine-Rich alpha-2 Glycoprotein 1 (LRG1) (AA 33-342) protein (His tag)LRG1 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Leucine-Rich alpha-2 Glycoprotein 1 (LRG1) (AA 37-347) protein (GST tag)LRG1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Leucine-Rich alpha-2 Glycoprotein 1 (LRG1) (AA 36-347) protein (His tag)LRG1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- Target
- LRG1 (Leucine-Rich alpha-2 Glycoprotein 1 (LRG1))
- Alternative Name
- LRG1 (LRG1 Products)
- Background
- LRG1, also known as leucine-rich alpha-2-glycoprotein, is a member of leucine-rich repeat (LRR) family. It is neutrophilic expressed during granulocyte differentiation. It has been shown to be involved in protein-protein interaction, signal transduction, and cell adhesion and development. It binds directly to the TGF-beta accessory receptor endoglin, which, in the presence of TGF-beta1, results in promotion of the pro-angiogenic Smad1/5/8 signaling pathway. It promotes proliferation and inhibits apoptosis in colorectal cancer cells via RUNX1 activation. It is a key physiological regulator of dendrite complexity of hippocampal pyramidal neurons. It physically interacts with TrkB and attenuates BDNF signaling. Recombinant human LRG1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 35.4 kDa (321aa)
- NCBI Accession
- NP_443204
- UniProt
- P02750
- Pathways
- Brown Fat Cell Differentiation
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