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CD226 Protein (CD226) (AA 19-252) (His tag)

Recombinant CD226 protein expressed in HEK-293 Cells.
Catalog No. ABIN6388274

Quick Overview for CD226 Protein (CD226) (AA 19-252) (His tag) (ABIN6388274)

Target

See all CD226 Proteins
CD226

Protein Type

Recombinant

Biological Activity

Active

Origin

  • 19
  • 5
  • 1
  • 1
  • 1
Cynomolgus

Source

  • 16
  • 5
  • 3
  • 2
  • 1
HEK-293 Cells

Purity

>90 % as determined by SDS-PAGE.
  • Protein Characteristics

    AA 19-252

    Purification tag / Conjugate

    This CD226 protein is labelled with His tag.

    Sequence

    AA 19-252

    Endotoxin Level

    Less than 1.0 EU per μg by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    PBS, pH 7.4

    Handling Advice

    Please avoid repeated freeze-thaw cycles.

    Storage

    -20 °C
  • Target

    CD226

    Alternative Name

    DNAM-1

    Background

    DNAX accessory molecule 1 (DNAM-1), a single-pass type I membrane protein, is also known as CD226 antigen and platelet and T cell activation antigen 1 (PTA1), which contains 2 Ig-like C2-type (immunoglobulin-like) domains. DNAM-1 is a ~65 kDa glycoprotein expressed on the surface of natural killer cells, platelets, monocytes and a subset of T cells. DNAM-1 mediates cellular adhesion to other cells bearing its ligands, CD112 and CD155, and cross-linking DNAM-1 with antibodies causes cellular activation. Furthermore, DNAM-1 can interact with PVR and PVRL2.

    Molecular Weight

    28.5 kDa

    NCBI Accession

    XP_005586537

    Pathways

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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