FOXO3 Protein (AA 372-673) (His-SUMO Tag)
Quick Overview for FOXO3 Protein (AA 372-673) (His-SUMO Tag) (ABIN6653946)
Target
See all FOXO3 ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 372-673
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Purification tag / Conjugate
- This FOXO3 protein is labelled with His-SUMO Tag.
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Sequence
- MAGTMNLNDG LTENLMDDLL DNITLPPSQP SPTGGLMQRS SSFPYTTKGS GLGSPTSSFN STVFGPSSLN SLRQSPMQTI QENKPATFSS MSHYGNQTLQ DLLTSDSLSH SDVMMTQSDP LMSQASTAVS AQNSRRNVML RNDPMMSFAA QPNQGSLVNQ NLLHHQHQTQ GALGGSRALS NSVSNMGLSE SSSLGSAKHQ QQSPVSQSMQ TLSDSLSGSS LYSTSANLPV MGHEKFPSDL DLDMFNGSLE CDMESIIRSE LMDADGLDFN FDSLISTQNV VGLNVGNFTG AKQASSQSWV PG
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Characteristics
- N-terminal 6xHis-SUMO-tagged
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Forkhead Box O3 (FOXO3) (AA 1-672) protein (His tag)
custom-made FOXO3 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Forkhead Box O3 (FOXO3) (AA 1-673) protein (His tag)custom-made FOXO3 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Forkhead Box O3 (FOXO3) (AA 1-673) protein (GST tag)FOXO3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Forkhead Box O3 (FOXO3) (AA 478-673) protein (His-IF2DI Tag)FOXO3 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Forkhead Box O3 (FOXO3) (AA 361-460) protein (GST tag)FOXO3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Forkhead Box O3 (FOXO3) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)FOXO3 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Forkhead Box O3 (FOXO3) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)FOXO3 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.1-2 mg/mL
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Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
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Storage
- -80 °C,4 °C,-20 °C
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Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- FOXO3 (Forkhead Box O3 (FOXO3))
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Alternative Name
- FOXO3
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Background
- Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation.
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Molecular Weight
- 48.1 kDa
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UniProt
- O43524
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Pathways
- Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis
Target
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