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IL-18 Protein (AA 36-192) (His tag)

Recombinant IL-18 protein expressed in Escherichia coli (E. coli).
Catalog No. ABIN666748

Quick Overview for IL-18 Protein (AA 36-192) (His tag) (ABIN666748)

Target

See all IL-18 (IL18) Proteins
IL-18 (IL18) (Interleukin 18 (IL18))

Protein Type

Recombinant

Origin

  • 21
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Human

Source

  • 31
  • 9
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  • 1
Escherichia coli (E. coli)

Application

SDS-PAGE (SDS)

Purity

> 90 % by SDS - PAGE
  • Protein Characteristics

    AA 36-192

    Purification tag / Conjugate

    This IL-18 protein is labelled with His tag.

    Characteristics

    Interleukin-18, 36-192aa, Mouse, His-tagged, Recombinant, E.coli
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  • Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/ml (determined by Bradford assay)

    Buffer

    In 20mM Tris-HCl pH 8.0 containing 10% glycerol

    Storage

    4 °C
  • Target

    IL-18 (IL18) (Interleukin 18 (IL18))

    Alternative Name

    Interleukin-18

    Background

    Interleukin 18 (IL-18), previously known as interferon-gamma (IFN-gamma)-inducing factor, is an activator of NK cells and a co-inducer of Th1 cytokines. IL-18 is produced from Kupffer cells, activated macrophages, keratinocytes, intestinal epithelial cells, osteoblasts, adrenal cortex cells and murine diencephalon. IL-18 was expressed in E.coli and purifed by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer. Synonyms: IL-18, IFN-gamma-inducing factor (IGIF), Interleukin-1 gamma , IL18, interleukin 18 (interferon-gamma-inducing factor), IGIF, IL1F4, IL-1g,. NCBI no.: NP_032386

    Molecular Weight

    20.4 kDa (178 aa), confirmed by MALDI-TOF.

    Pathways

    Cellular Response to Molecule of Bacterial Origin, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome
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