Chromogranin A Protein (CHGA) (AA 19-131)
Quick Overview for Chromogranin A Protein (CHGA) (AA 19-131) (ABIN666766)
Target
See all Chromogranin A (CHGA) ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- AA 19-131
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Sequence
- MLPVNSPMNK GDTEVMKCIV EVISDTLSKP SPMPVSQECF ETLRGDERIL SILRHQNLLK ELQDLALQGA KERAHQQKKH SGFEDELSEV LENQSSQAEL KEAVEEPSSK DVME
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Characteristics
- Vasostatin 2 , 19-131aa, Human, Recombinant, E.coli
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Purification
- > 95% by SDS-PAGE
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Endotoxin Level
- < 1 EU per 1ug of protein (determined by LAL method)
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Chromogranin A (CHGA) (AA 165-435) protein (His tag)
CHGA Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Chromogranin A (CHGA) (AA 1-457) protein (GST tag)CHGA Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Chromogranin A (CHGA) (AA 19-457) protein (His tag)CHGA Origin: Human Host: Escherichia coli (E. coli) Recombinant > 80 % SDS
Chromogranin A (CHGA) (AA 19-457) protein (His tag)CHGA Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 85 % SDS
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 20 mM Tris-HCl buffer ( pH 8.0) containing 10 % glycerol
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- Chromogranin A (CHGA)
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Alternative Name
- Chromogranin A/CHGA
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Background
- Vasostatin 2 is the N-terminal fragment (19-131 aa) derived from the cleavage of chromogranin A (CgA) which is a member of the chromogranin/secretogranin (granins) family of neuroendocrine secretory proteins. Vasostatin 2 has been shown to exert several biological activities on several tissues and organs and exerts a large spectrum of homeostatic actions, including antifungal and antimicrobial effect, modulation of cell adhesion, and inhibition of parathyroid hormone secretion. Recombinant human Vasostatin 2 protein was expressed in E. coli and purified by using conventional chromatography techniques.
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Molecular Weight
- 12.8 kDa (114aa) confirmed by MALDI-TOF
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NCBI Accession
- NP_001266
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Pathways
- Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling
Target
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