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Chromogranin A Protein (CHGA) (AA 457-717) (His tag)

CHGA Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >90 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7505366
  • Target See all Chromogranin A (CHGA) Proteins
    Chromogranin A (CHGA)
    Protein Type
    Recombinant
    Protein Characteristics
    AA 457-717
    Origin
    • 9
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Mouse
    Source
    • 9
    • 6
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This Chromogranin A protein is labelled with His tag.
    Sequence
    Ile457-Leu717
    Characteristics
    A DNA sequence encoding theMouse Chromogranin-A/Chga(P26339) (457Ile-717Leu) was expressed with a polyhistidine tag at the N-terminus.
    Purity
    >90 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product CHGA Protein
  • Comment

    used as Immunogen for (ABIN6999910, ABIN7234262, ABIN7234263 and ABIN7234264)

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Expiry Date
    12 months
  • Target
    Chromogranin A (CHGA)
    Alternative Name
    Chromogranin-A (CHGA Products)
    Synonyms
    CGA Protein, CG-ALPHA Protein, FSHA Protein, GPHA1 Protein, GPHa Protein, HCG Protein, LHA Protein, TSHA Protein, ChrA Protein, fj05f09 Protein, si:dkey-177p2.2 Protein, wu:fj05f09 Protein, zgc:101749 Protein, zgc:56075 Protein, CHGA Protein, cgA Protein, chga Protein, chromogranin A Protein, glycoprotein hormones, alpha polypeptide Protein, uncharacterized CHGA Protein, chromogranin A S homeolog Protein, CHGA Protein, CGA Protein, Chga Protein, chga Protein, chga.S Protein
    Background

    Background: Pancreastatin: Strongly inhibits glucose induced insulin release from the pancreas.Catestatin: Inhibits catecholamine release from chromaffin cells and noradrenergic neurons by acting as a non-competitive nicotinic cholinergic antagonist. Can induce mast cell migration, degranulation and production of cytokines and chemokines.Serpinin: Regulates granule biogenesis in endocrine cells by up-regulating the transcription of protease nexin 1 (SERPINE2) via a cAMP-PKA-SP1 pathway. This leads to inhibition of granule protein degradation in the Golgi complex which in turn promotes granule formation . Pyroglutaminated (pGlu)-serpinin exerts an antiapoptotic effect on cells exposed to oxidative stress .

    Synonym: beta Granin,betagranin (N-terminal fragment of chromogranin A),catestatin,CgA,CHG A,Chga,chromofungin,Chromogranin A,Chromogranin A parathyroid secretory protein 1,Chromogranin A precursor,ChromograninA,CMGA,ER-37,Pancreastatin,Parastatin,Parathyroid secretory protein 1,Pituitary secretory protein I,Secretory protein I,SP I,SP-I,SP1,SPI,Vasostatin,Vasostatin I,Vasostatin II

    Molecular Weight
    31 kDa
    UniProt
    P26339
    Pathways
    Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling
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