BMP5 Protein (AA 317-454)

Catalog No. ABIN666779

This Recombinant BMP5 protein is produced in Escherichia coli (E. coli).

Quick Overview for BMP5 Protein (AA 317-454) (ABIN666779)

Target: BMP5 (Bone Morphogenetic Protein 5 (BMP5))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Purity: > 95 %

Product Details

Protein Characteristics: AA 317-454

Sequence: MAANKRKNQN RNKSSSHQDS SRMSSVGDYN TSEQKQACKK HELYVSFRDL GWQDWIIAPE GYAAFYCDGE CSFPLNAHMN ATNHAIVQTL VHLMFPDHVP KPCCAPTKLN AISVLYFDDS SNVILKKYRN MVVRSCGCH

Characteristics: BMP5, 317-454 aa,Human, Recombinant, E.coli

Purification: > 95% by SDS-PAGE

Endotoxin Level: < 1 EU per 1ug of protein (determined by LAL method)

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 10 mM Sodium Citrate buffer ( pH 3.5) containing 10 % glycerol

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details

Target: BMP5 (Bone Morphogenetic Protein 5 (BMP5))

Alternative Name: BMP-5

Background: BMP5 is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. BMP5 may play a role in certain cancers. This protein may act as an important signaling molecule within the trabecular meshwork and optic nerve head, and may play a potential role in glaucoma pathogenesis. Recombinant BMP5 was expressed in E. coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.

Molecular Weight: 15.7 kDa (139aa) confirmed by MALDI-TOF

NCBI Accession: NP_066551

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process