BMP5 Protein
-
- Target See all BMP5 Proteins
- BMP5 (Bone Morphogenetic Protein 5 (BMP5))
- Protein Type
- Recombinant
- Biological Activity
- Active
-
Origin
- Human
-
Source
- CHO Cells
- Sequence
- AANKRKNQNR NKSSSHQDSS RMSSVGDYNT SEQKQACKKH ELYVSFRDLG WQDWIIAPEG YAAFYCDGEC SFPLNAHMNA TNHAIVQTLV HLMFPDHVPK PCCAPTKLNA ISVLYFDDSS NVILKKYRNM VVRSCGCH
- Characteristics
- Biological activity was determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 1.0-2.0 μg/mL.
- Purity
- < 95 % by SDS-PAGE gel and HPLC analyses.
- Endotoxin Level
- Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
- Top Product
- Discover our top product BMP5 Protein
-
Bone Morphogenetic Protein 5 (BMP5) (AA 341-440) protein (GST tag)
BMP5 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Bone Morphogenetic Protein 5 (BMP5) (AA 323-422) protein (GST tag)BMP5 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Bone Morphogenetic Protein 5 (BMP5) (AA 323-454) protein (GST tag)BMP5 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Bone Morphogenetic Protein 5 (BMP5) (AA 341-454) protein (GST tag)BMP5 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Bone Morphogenetic Protein 5 (BMP5) (AA 317-454) proteinBMP5 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Bone Morphogenetic Protein 5 (BMP5) (AA 1-454) protein (GST tag)BMP5 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Bone Morphogenetic Protein 5 (BMP5) (AA 317-454) protein (His tag)Crystallography grade BMP5 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Bone Morphogenetic Protein 5 (BMP5) (AA 315-452) protein (His tag)Crystallography grade BMP5 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Handling Advice
- As with any protein, exposing BMP-5 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
- Storage
- -20 °C
- Storage Comment
- The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted BMP-5 stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
- Expiry Date
- 24 months
-
- Target
- BMP5 (Bone Morphogenetic Protein 5 (BMP5))
- Alternative Name
- BMP-5 (BMP5 Products)
- Synonyms
- bmp5l Protein, hm:zehl0669 Protein, zehl0669 Protein, zgc:64230 Protein, BMP5 Protein, AU023399 Protein, se Protein, bone morphogenetic protein 5 Protein, bmp5 Protein, BMP5 Protein, LOC100539495 Protein, Bmp5 Protein
- Background
- TGF-beta family members are key modulators of cell proliferation, differentiation, matrix synthesis, and apoptosis. As implied by their name, BMPs initiate, promote, and regulate the development, growth and remodeling of bone and cartilage. In addition to this role, BMPs are also involved in prenatal development and postnatal growth, remodeling and maintenance of a variety of other tissues and organs. BMP-5 is expressed in the nervous system, lung and liver. It is a known regulator for dendritic growth in sympathetic neurons. BMP-5 is a 454 amino acid precursor protein that is cleaved to release the biologically active C-terminal mature protein. Recombinant human BMP-5 is a 31.2 kDa homodimeric disulfide-linked protein consisting of two identical 138 amino acid chains.
- Gene ID
- 653
- NCBI Accession
- NP_066551
- OMIM
- 10835091
- UniProt
- P22003
- Pathways
- Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process
-
