BLVRB Protein (AA 1-206)

Catalog No. ABIN666868

Recombinant BLVRB protein expressed in Escherichia coli (E. coli).

Quick Overview for BLVRB Protein (AA 1-206) (ABIN666868)

Target: BLVRB (Flavin Reductase (BLVRB))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Purity: > 95 %

Product Details

Protein Characteristics: AA 1-206

Sequence: MAVKKIAIFG ATGQTGLTTL AQAVQAGYEV TVLVRDSSRL PSEGPRPAHV VVGDVLQAAD VDKTVAGQDA VIVLLGTRND LSPTTVMSEG ARNIVAAMKA HGVDKVVACT SAFLLWDPTK VPPRLQAVTD DHIRMHKVLR ESGLKYVAVM PPHIGDQPLT GAYTVTLDGR GPSRVISKHD LGHFMLRCLT TDEYDGHSTY PSHQYQ

Characteristics: Biliverdin reductase B, 1-206aa, Human, Recombinant, E.coli

Purification: > 95% by SDS-PAGE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 20 mM Tris-HCl buffer ( pH 8.5) containing 10 % glycerol, 1 mM DTT

Handling Advice: Avoid repeated freezing and thawing cycles

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details

Target: BLVRB (Flavin Reductase (BLVRB))

Alternative Name: Biliverdin Reductase B/BLVRB

Background: Biliverdin reductase B (BLVRB) is an enzyme (EC 1. 3. 1. 24) that converts biliverdin to bilirubin, converting a double-bond between the second and third pyrrole ring into a single-bond. BLVRB is found that major erythrocytic heme catabolic pathway in humans and most mammalian species. Biliverdin reductase is abundantly expressed in kidney, spleen, liver and brain as well as at lower levels in the thymus and minimal levels being detected in testis. Recombinant BLVRB protein was expressed in E. coli and purified by using conventional chromatography techniques.

Molecular Weight: 22.1 kDa (206aa) confirmed by MALDI-TOF

NCBI Accession: NP_000704