IFNA2 Protein (AA 24-188)
Quick Overview for IFNA2 Protein (AA 24-188) (ABIN667040)
Target
See all IFNA2 ProteinsProtein Type
Biological Activity
Origin
Source
Application
Purity
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Protein Characteristics
- AA 24-188
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Sequence
- MCDLPQTHSL GSRRTLMLLA QMRRISLFSC LKDRHDFGFP QEEFGNQFQK AETIPVLHEM IQQIFNLFST KDSSAAWDET LLDKFYTELY QQLNDLEACV IQGVGVTETP LMKEDSILAV RKYFQRITLY LKEKKYSPCA WEVVRAEIMR SFSLSTNLQE SLRSKE
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Characteristics
- Interferon alpha-2b (24-188) Human, Recombinant, E.coli
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Purification
- > 95% by SDS-PAGE
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Endotoxin Level
- < 1 EU per 1ug of protein (determined by LAL method)
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Biological Activity Comment
- Measured by its binding ability in a functional ELISA with Human IFN-alpha/beta R2 (CAT# ATGP3952) in the presence of Human IFN-alpha/beta R1 (CAT# ATGP3894).
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Interferon, alpha 2 (IFNA2) (Active) protein
IFNA2 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Interferon, alpha 2 (IFNA2) proteinIFNA2 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE
Interferon, alpha 2 (IFNA2) (AA 24-188) protein (Fc Tag)IFNA2 Origin: Human Host: Mammalian Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Interferon, alpha 2 (IFNA2) (AA 1-188) protein (GST tag)IFNA2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Phosphate-Buffered Saline ( pH 7.4), 10 % glycerol
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- IFNA2 (Interferon, alpha 2 (IFNA2))
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Alternative Name
- IFN-alpha 2/IFNA2
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Background
- Interferon induces a variety of effects on target cells including antiviral, antiproliferative, and immunomodulatory activities. Interferon alpha-2b can either inhibit or enhance immune cell activity within the tightly regulated microenvironment of inflammation, depending upon the concentration of the cytokine and the activation stage of the cell. Interferon alpha-2b was expressed in E. coli and purifed by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
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Molecular Weight
- 19.4 kDa (166aa) confirmed by MALDI-TOF
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NCBI Accession
- NP_000596
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Pathways
- JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Hepatitis C
Target
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