Ferric Uptake Regulator (AA 1-148) Protein

Catalog No. ABIN667071

This Recombinant Ferric Uptake Regulator protein is expressed in Escherichia coli (E. coli).

Quick Overview for Ferric Uptake Regulator (AA 1-148) Protein (ABIN667071)

Target: Ferric Uptake Regulator

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Purity: > 95 %

Product Details

Protein Characteristics: AA 1-148

Sequence: MTDNNTALKK AGLKVTLPRL KILEVLQEPD NHHVSAEDLY KRLIDMGEEI GLATVYRVLN QFDDAGIVTR HNFEGGKSVF ELTQQHHHDH LICLDCGKVI EFSDDSIEAR QREIAAKHGI RLTNHSLYLY GHCAEGDCRE DEHAHEGK

Characteristics: Ferric uptake regulator(FUR), 1-148 aa E.coli, Recombinant, E.coli

Purification: > 95% by SDS-PAGE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 20 mM Tris-HCl buffer ( pH 8.0) containing 2 mM CaCl2, 100 mM NaCl

Handling Advice: Avoid repeated freezing and thawing cycles

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details

Target: Ferric Uptake Regulator

Alternative Name: Ferric uptake regulator/FuR

Background: Fur (ferric uptake regulator) protein is a DNA-binding protein which regulates iron-responsive genes. Fur is a small, 17- kDa, global transcriptional repressor that in the presence of iron regulates functions as diverse as iron acquisition, oxidative stress, and virulence. In Escherichia coli, members of the Fur family regulate the expression of more than 100 genes that function in processes as varied as the biosynthesis and transport of siderophores, the expression of virulence factors, the alleviation of oxidative and NO-induced stress, and the inhibition of ferritin production through the expression of RyhB. Recombinant FuR was expressed in E. coli and purified by using conventional chromatography techniques.

Molecular Weight: 16.7 kDa (148aa) confirmed by MALDI-TOF

NCBI Accession: NP_415209