FKBP2 Protein (AA 22-142)
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- Target See all FKBP2 Proteins
- FKBP2 (FK506 Binding Protein 2, 13kDa (FKBP2))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 22-142
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- SDS-PAGE (SDS), Enzyme Activity Assay (EAA)
- Sequence
- MATGAEGKRK LQIGVKKRVD HCPIKSRKGD VLHMHYTGKL EDGTEFDSSL PQNQPFVFSL GTGQVIKGWD QGLLGMCEGE KRKLVIPSEL GYGERGAPPK IPGGATLVFE VELLKIERRT EL
- Characteristics
- FKBP2, 22-142aa, Human, E.coli
- Purity
- > 90% by SDS-PAGE
- Endotoxin Level
- < 1 EU per 1ug of protein (determined by LAL method)
- Biological Activity Comment
- Specific activity is > 700nmol/min/mg, and is defined as the amount of enzyme that cleaves 1nmol of suc-AAPF-pNA per minute at 37C in Tris-HCl pH 8.0 using chymotrypsin.
- Top Product
- Discover our top product FKBP2 Protein
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FK506 Binding Protein 2, 13kDa (FKBP2) (AA 22-142) protein (His tag)
FKBP2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
FK506 Binding Protein 2, 13kDa (FKBP2) (AA 1-142) protein (GST tag)FKBP2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
FK506 Binding Protein 2, 13kDa (FKBP2) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)FKBP2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
FK506 Binding Protein 2, 13kDa (FKBP2) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)FKBP2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
FK506 Binding Protein 2, 13kDa (FKBP2) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)FKBP2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. In 20mM Tris buffer(pH 8.0) containing 10% glycerol, 1mM DTT.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- Target
- FKBP2 (FK506 Binding Protein 2, 13kDa (FKBP2))
- Alternative Name
- FKBP13/FKBP2 (FKBP2 Products)
- Background
- FKBP2 is peptidyl proline isomerase enzyme and a member of the immunophilin protein family. This protein is predominantly expressed in thymus and T cells and plays a role in immunoregulation and basic cellular processes involving protein folding and trafficking. It is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. FKBP2 is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. Recombinant FKBP2 protein was expressed in E. coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 13.4 kDa (122aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_001128680
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