CAB39 Protein (AA 1-341) (His tag)
Quick Overview for CAB39 Protein (AA 1-341) (His tag) (ABIN667796)
Target
See all CAB39 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- AA 1-341
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Purification tag / Conjugate
- This CAB39 protein is labelled with His tag.
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Sequence
- MGSSHHHHHH SSGLVPRGSH MPFPFGKSHK SPADIVKNLK ESMAVLEKQD ISDKKAEKAT EEVSKNLVAM KEILYGTNEK EPQTEAVAQL AQELYNSGLL STLVADLQLI DFEGKKDVAQ IFNNILRRQI GTRTPTVEYI CTQQNILFML LKGYESPEIA LNCGIMLREC IRHEPLAKII LWSEQFYDFF RYVEMSTFDI ASDAFATFKD LLTRHKLLSA EFLEQHYDRF FSEYEKLLHS ENYVTKRQSL KLLGELLLDR HNFTIMTKYI SKPENLKLMM NLLRDKSRNI QFEAFHVFKV FVANPNKTQP ILDILLKNQA KLIEFLSKFQ NDRTEDEQFN DEKTYLVKQI RDLKRPAQQE A
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Characteristics
- CAB39, 1-341aa, Human, His tag, E.coli
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Purification
- > 90% by SDS-PAGE
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 20 mM Tris-HCl buffer ( pH 8.0) containing 1 mM DTT, 10 % glycerol
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- CAB39 (Calcium Binding Protein 39 (CAB39))
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Alternative Name
- CAB39
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Background
- Calcium binding protein 39, also known as CAB39, is a 40- kDa protein that, together with the STE20-related adaptor-alpha (STRAD alpha) pseudo kinase, forms a regulatory complex capable of stimulating the activity of the LKB1 tumor suppressor protein kinase. Also CAB39 may function as a scaffolding component of the STK11/STRAD complex and regulates STK11 activity and cellular localization. Recombinant human CAB39, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques
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Molecular Weight
- 42 kDa (361aa) confirmed by MALDI-TOF
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NCBI Accession
- NP_057373
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Pathways
- AMPK Signaling
Target
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