TSSC4 Protein (AA 1-329) (His tag)

Catalog No. ABIN668006

This Recombinant TSSC4 protein is produced in Escherichia coli (E. coli).

Quick Overview for TSSC4 Protein (AA 1-329) (His tag) (ABIN668006)

Target: TSSC4 (Tumor Suppressing Subtransferable Candidate 4 (TSSC4))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Purity: > 90 %

Product Details

Protein Characteristics: AA 1-329

Purification tag / Conjugate: This TSSC4 protein is labelled with His tag.

Sequence: MAEAGT GEPSPSVEGE HGTEYDTLPS DTVSLSDSDS DLSLPGGAEV EALSPMGLPG EEDSGPDEPP SPPSGLLPAT VQPFHLRGMS STFSQRSRDI FDCLEGAARR APSSVAHTSM SDNGGFKRPL APSGRSPVEG LGRAHRSPAS PRVPPVPDYV AHPERWTKYS LEDVTEVSEQ SNQATALAFL GSQSLAAPTD CVSSFNQDPS SCGEGRVIFT KPVRGVEARH ERKRVLGKVG EPGRGGLGNP ATDRGEGPVE LAHLAGPGSP EAEEWGSPHG GLQEVEALSG SVHSGSVPGL PPVETVGFHG SRKRSRDHFR NKSSSPEDPG AEV

Characteristics: TSSC4, 1-329aa, Human, His tag, E.coli

Purification: > 90% by SDS-PAGE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: 20 mM Tris-HCl buffer ( pH 8.0) containing 2 mM DTT,20 % glycerol, 200 mM NaCl

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details

Target: TSSC4 (Tumor Suppressing Subtransferable Candidate 4 (TSSC4))

Alternative Name: TSSC4

Background: TSSC4 (tumor suppressing subtransferable candidate 4), also known as tumor suppressing STF cDNA 4 protein, belongs to the TSSC4 family. This protein is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15. 5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. It plays a role in malignancies and disease that involve this region as well as hematopoietic cell function This protein was widely expressed in nearly all adult tissues, TSSC4 is also found in fetal liver, lung, kidney and brain. Recombinant human TSSC4 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Molecular Weight: 36.8 kDa (353aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)