CCL17 Protein

Catalog No. ABIN6699602

Supplier Product No.: 009-001-w25-0100

This Recombinant CCL17 protein is expressed in Escherichia coli (E. coli).

Quick Overview for CCL17 Protein (ABIN6699602)

Target: CCL17 (Chemokine (C-C Motif) Ligand 17 (CCL17))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Purity: 98,00%

Product Details

Supplier Product No.: 009-001-w25-0100

Supplier: Rockland

Purpose: Human TARC (CCL17) Recombinant Protein

Purification: TARC (CCL17) purity was determined to be greater than 98% as determined by HpLC, analysis by UV-Spectroscopy at 280nm, and by reducing and non-reducing SDS-pAGE.

Endotoxin Level: Measured by LAL is typically ≤ 1 EU/μg protein.

Biological Activity Comment: The activity is determined by the ability to chemoattract human T cells at 2-40 ng/mL.

Application Details

Application Notes:

Application Note: TARC Recombinant Protein is suitable as a control for polyclonal or monoclonal anti-TARC in immunological assays.

Other: User Optimized

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution:

Reconstitution_Buffer: Restore with deionized water (or equivalent)

Reconstitution_Volume: 100 μL

Buffer:

Buffer: 0.1 % Trifluoroacetic acid

Stabilizer: None

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Store vial at 4° C prior to restoration. Dilute only prior to immediate use. Maintain sterility. This product DOES NOT contain preservative. DO NOT VORTEX. We recommend adding a carrier protein such as HSA or BSA to 0.1% (i.e. 1.0 mg/mL). For best results aliquot contents and freeze at -20° C or colder. Avoid cycles of freezing and thawing. Centrifuge vial before each opening to dislodge contents from the cap and to clarify if contents are not clear after standing at room temperature.

Expiry Date: 6 months

Target Details

Target: CCL17 (Chemokine (C-C Motif) Ligand 17 (CCL17))

Alternative Name: CCL17

Background:

Synonyms: Thymus and activation regulated chemokine, ABCD-2, SCYA17, CC chemokine TARC, Small-inducible cytokine A17

Background: Thymus and activation regulated chemokine (TARC), also known as CCL17, is a chemokine produced by thymus tissue constitutively and activated PBMCs (mainly DCs). TARC signals through the CCR4 receptor to induce chemotaxis of Th2 cells. TARC is thought to be important in asthma and allergic diseases, along with bacterial and viral infections. Recombinant human TARC is a non-glycosylated protein, containing 71 amino acids, with a molecular weight of 8.1 kDa.

UniProt: Q92583