CXCL2 Protein

Catalog No. ABIN6699695

Supplier Product No.: 009-001-v16-0010

Product Details

Target: CXCL2 (Chemokine (C-X-C Motif) Ligand 2 (CXCL2))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Supplier Product No.: 009-001-v16-0010

Supplier: Rockland

Purpose: Human Gro-beta (CXCL2) Recombinant Protein

Purification: Gro-beta (CXCL2) purity was determined to be greater than 98% as determined by HpLC and by reducing and non-reducing SDS-pAGE.

Purity: 98,00%

Endotoxin Level: Measured by LAL is typically ≤ 1 EU/μg protein.

Biological Activity Comment: The activity is determined by the ability to chemoattract human neutrophils at concentrations between 10-100 ng/mL.

Application Details

Application Notes:

Other: User Optimized

Application_Note: Gro-beta Recombinant Protein has been tested by biological activity and is suitable as a control for polyclonal or monoclonal anti-Gro-beta in immunological assays.

Comment:

Suggested_Applications: Cellular Assay

Other_Performance_Data:

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution:

Reconstitution_Buffer: Restore with deionized water (or equivalent)

Reconstitution_Volume: 10 μL (10-100 μL)

Buffer:

Buffer: 0.1 % Trifluoroacetic acid

Stabilizer: None

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Store vial at 4° C prior to restoration. Dilute only prior to immediate use. Maintain sterility. This product DOES NOT contain preservative. DO NOT VORTEX. We recommend adding a carrier protein such as HSA or BSA to 0.1% (i.e. 1.0 mg/mL). For best results aliquot contents and freeze at -20° C or colder. Avoid cycles of freezing and thawing. Centrifuge vial before each opening to dislodge contents from the cap and to clarify if contents are not clear after standing at room temperature.

Expiry Date: 6 months

Target Details

Target: CXCL2 (Chemokine (C-X-C Motif) Ligand 2 (CXCL2))

Alternative Name: CXCL2 (CXCL2 Products)

Background:

Synonyms: MGSAβ, Macrophage inflammatory protein 2-alpha (MIP-2α), Growth-regulated protein beta (Gro-beta), GRO2

Background: Three human MGSA/GRO genes encode 3 highly related chemokines, MGSA/GRO α, -β and -g. All 3 MGSA/GRO proteins bind to the same receptors, but with differing affinities, and stimulate a number of biological responses including chemotaxis, angiogenesis, and growth regulation. Recombinant human GROβ is a non-glycosylated protein, containing 73 amino acids, with a molecular weight of 7.9 kDa.

UniProt: P19875

Pathways: Cellular Response to Molecule of Bacterial Origin