B7-H3 (4Ig) (AA 27-461) (Active) protein (His tag)

Catalog No. ABIN6809952

Recombinant B7-H3 (4Ig) protein expressed in HEK-293 Cells.

Quick Overview for B7-H3 (4Ig) (AA 27-461) (Active) protein (His tag) (ABIN6809952)

Target: B7-H3 (4Ig)

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: HEK-293 Cells

Purity: >95 % as determined by SDS-PAGE.

Product Details

Protein Characteristics: AA 27-461

Purification tag / Conjugate: His tag

Sequence: AA 27-461

Endotoxin Level: Less than 1.0 EU per μg by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: PBS, pH 7.4

Handling Advice: Please avoid repeated freeze-thaw cycles.

Storage: -20 °C

Target Details

Target: B7-H3 (4Ig)

Background: Human B7 homolog 3 (B7-H3) is a member of the B7 family of immune proteins that provide signals for the regulation of immune responses. Other family members include B7-1, B7-2, B7-H1/PD-L1, B7-H2, and PD-L2. B7 family proteins are type I transmembrane immunoglobulin (Ig) superfamily members that contain extracellular Ig V-like and Ig C-like domains with a short cytoplasmic tail. Termed 4IgB7-H3 or B7-H3b, this molecule has two additional Ig-like domains (one V-type and one C-type) and shows a ubiquituous expression pattern.

Molecular Weight: 48.5 kDa

NCBI Accession: NP_001019907