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C5A Protein (AA 679-751) (Fc Tag)

C5a Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Catalog No. ABIN6938863
  • Target See all C5A (C5a) Proteins
    C5A (C5a) (Complement Component 5a (C5a))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Protein Characteristics
    AA 679-751
    Origin
    • 5
    • 4
    • 4
    • 2
    • 2
    Human
    Source
    • 16
    HEK-293 Cells
    Purification tag / Conjugate
    This C5A protein is labelled with Fc Tag.
    Purity
    >90 % as determined by SDS-PAGE.
    Endotoxin Level
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product C5a Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Tris with Glycine, Arginine and NaCl,  pH 7.5
    Storage
    -20 °C
  • Target
    C5A (C5a) (Complement Component 5a (C5a))
    Alternative Name
    Complement Component C5a (C5a Products)
    Synonyms
    C5a Protein, C5b Protein, CPAMD4 Protein, Hc Protein, RGD1561905 Protein, complement C5 Protein, C5 Protein
    Background
    Complement Component C5a (C5a) is also known as C5,and is a protein fragment released from complement component C5.,is a potent chemotactic factor for human peripheral blood neutrophils and monocytes, and is believed to play an important role in a number of inflammatory conditions. There are several functions in the below: C5a is an anaphylatoxin, causing the release of histamine from mast cells, C5a is effective leukocyte chemoattractants, causing the accumulation of white blood cells, especially neutrophil granulocytes, at sites of complement activation, C5a activates white blood cells by increasing avidity for white blood cell integrins and upregulating the Lipoxygenase pathway for arachidonic acid metabolism, C5a is a powerful inflammatory mediator, and seems to be a key factor in the development of pathology of many inflammatory diseases involving the complement system, C5a modulates balance between activating versus inhibitory IgG Fc receptors on leukocytes, thereby enhancing autoimmune response.
    Molecular Weight
    34.6 kDa
    NCBI Accession
    XP_015292262
    Pathways
    Complement System, Carbohydrate Homeostasis
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