IL-5 Protein (AA 20-134) (His tag)
Quick Overview for IL-5 Protein (AA 20-134) (His tag) (ABIN6938893)
Target
See all IL-5 (IL5) ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 20-134
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Purification tag / Conjugate
- This IL-5 protein is labelled with His tag.
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Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
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Interleukin 5 (IL5) (AA 20-134) protein (His-Avi Tag)
IL5 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 5 (IL5) (AA 20-134) (Active) protein (Biotin,His-Avi Tag)IL5 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Interleukin 5 (IL5) (AA 20-134) protein (Fc Tag)IL5 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ADA, AM, IA, ScA
Interleukin 5 (IL5) (AA 20-134) protein (His tag)IL5 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ADA, AM, IA, ScA
Interleukin 5 (IL5) (AA 20-134) (Active) protein (His tag)IL5 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Interleukin 5 (IL5) (AA 21-133) (Active) protein (Biotin,His-Avi Tag)IL5 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
Interleukin 5 (IL5) (AA 21-133) (Active) protein (His-Avi Tag)IL5 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
Interleukin 5 (IL5) (Active) proteinIL5 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Interleukin 5 (IL5) (AA 1-134) protein (GST tag)IL5 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Interleukin 5 (IL5) protein (mFc Tag)IL5 Origin: Human Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Storage
- -20 °C
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- IL-5 (IL5) (Interleukin 5 (IL5))
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Alternative Name
- IL-5
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Background
- Interleukin 5 (IL5) is an interleukin produced by type-2 T helper cells and mast cells. IL-5 is a 115-amino acid (in human, 133 in the mouse) -long TH2 cytokine that is part of the hematopoietic family. Unlike other members of this cytokine family (namely interleukin 3 and GM-CSF), this glycoprotein in its active form is a homodimer. Interleukin-5 has long been associated with the cause of several allergic diseases including allergic rhinitis and asthma, wherein a large increase in the number of circulating, airway tissue, and induced sputum eosinophils have been observed. Given the high concordance of eosinophils and, in particular, allergic asthma pathology, it has been widely speculated that eosinophils have an important role in the pathology of this disease. Drugs that target IL-5 are mepolizumab and reslizumab.
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Molecular Weight
- 15.0 kDa
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NCBI Accession
- NP_000870
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Pathways
- JAK-STAT Signaling, Positive Regulation of Peptide Hormone Secretion, Production of Molecular Mediator of Immune Response, Feeding Behaviour
Target
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