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CCL14 Protein (AA 28-93) (Biotin)

CCL14 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 97 % by SDS PAGE CMA Active
Catalog No. ABIN6952143
  • Target See all CCL14 Proteins
    CCL14 (Chemokine (C-C Motif) Ligand 14 (CCL14))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Protein Characteristics
    AA 28-93
    Origin
    Human
    Source
    • 12
    • 3
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This CCL14 protein is labelled with Biotin.
    Application
    Cell Migration Assay (CMA)
    Sequence
    GPYHPSECCF TYTTYKIPRQ RIMDYYETNS QCSKPGIVFI TKRGHSVCTN PSDKWVQDYI KDMKEN
    Characteristics
    Biotininylated Recombinant Human CCL14 (HCC-1)
    Purity
    > 97 % by SDS PAGE
    Endotoxin Level
    <0.01 EU per 1μg of the protein by the LAL method
    Biological Activity Comment
    EC50 = 0.2-0.4 nM determined by migration assay with cells expressing recombinant CCR1
    Top Product
    Discover our top product CCL14 Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Spin tube prior to resuspending. Recommended at 100 μg/mL in sterile water
    Storage
    -20 °C,-80 °C
    Storage Comment
    12 months from date of receipt, -20 to -70 °C as supplied.
    Suggest to use immediately after reconstitution
    1 month at -20 to -70 °C under sterile conditions after reconstitution.
    Expiry Date
    12 months
  • Target
    CCL14 (Chemokine (C-C Motif) Ligand 14 (CCL14))
    Alternative Name
    CCL14 (HCC-1) (CCL14 Products)
    Synonyms
    CCL14 Protein, CC-1 Protein, CC-3 Protein, CKB1 Protein, HCC-1 Protein, HCC-1(1-74) Protein, HCC-1/HCC-3 Protein, HCC-3 Protein, MCIF Protein, NCC-2 Protein, NCC2 Protein, SCYA14 Protein, SCYL2 Protein, SY14 Protein, C-C motif chemokine ligand 14 Protein, C-C motif chemokine 14 Protein, chemokine (C-C motif) ligand 14 Protein, CCL14 Protein, Ccl14 Protein, LOC480603 Protein, LOC101115044 Protein
    Background
    Hemofiltrate CC chemokine-1(HCC-1/CCL14) is endogeneously expressed by numerous tissues. Upon processing of the N terminal residues of the full length HCC-1 by the uPA-plasmin system, the active form of HCC-1 (made by ChemoTactics) is a strong agonist for CCR1, CCR5 and to a lesser extent CCR3, and causes chemotaxis of different types of leukocytes. The active form of HCC-1 is also shown as a potent inhibitor of HIV entry.
    Molecular Weight
    10.220 kDa
    UniProt
    Q16627
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