CCL28 Protein (AA 23-127) (Biotin)

Catalog No. ABIN6952175

Recombinant CCL28 protein expressed in Escherichia coli (E. coli).

Quick Overview for CCL28 Protein (AA 23-127) (Biotin) (ABIN6952175)

Target: CCL28 (Chemokine (C-C Motif) Ligand 28 (CCL28))

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: Escherichia coli (E. coli)

Application: Cell Migration Assay (CMA)

Purity: > 97 % by SDS PAGE

Product Details

Protein Characteristics: AA 23-127

Purification tag / Conjugate: This CCL28 protein is labelled with Biotin.

Sequence: ILPIASSCCT EVSHHISRRL LERVNMCRIQ RADGDCDLAA VILHVKRRRI CVSPHNHTVK QWMKVQAAKK NGKGNVCHRK KHHGKRNSNR AHQGKHETYG HKTPY

Characteristics: Biotininylated Recombinant Human CCL28 (MEC)

Endotoxin Level: <0.01 EU per 1μg of the protein by the LAL method

Biological Activity Comment: EC50 = 40-60 nM determined by migration assay with cells expressing recombinant CCR10

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Spin tube prior to resuspending. Recommended at 100 μg/mL in sterile water

Storage: -20 °C,-80 °C

Storage Comment: 12 months from date of receipt, -20 to -70 °C as supplied.
Suggest to use immediately after reconstitution
1 month at -20 to -70 °C under sterile conditions after reconstitution.

Expiry Date: 12 months

Target Details

Target: CCL28 (Chemokine (C-C Motif) Ligand 28 (CCL28))

Alternative Name: CCL28 (MEC)

Background: Mucosae-associated epithelial chemokine (MEC/CCL28) is secreted by epithelial cells of gastrointestinal and nonintestinal mucosal cells, and regulates chemotaxis of cells expressing surface receptors CCR3 and CCR10. It shows broad-spectrum antibacterial activities, and could also be useful in vaccination of HIV infection.

Molecular Weight: 14.491 kDa

UniProt: Q9NRJ3