SARS-CoV-2 Spike (ECD) (Active) protein (His tag)

Details for Product No. ABIN6952734
Protein Name
  • E2
  • Surface Glycoprotein
  • S
Protein Characteristics
ECD
4
3
2
1
Origin
SARS Coronavirus-2 (SARS-CoV-2)
17
Source
HEK-293 Cells
12
2
1
1
1
Protein Type
Recombinant
Biological Activity
Active
Purification tag / Conjugate
This SARS-CoV-2 Spike protein is labelled with His tag.
Application
Functional Studies (Func), SDS-PAGE (SDS)
Options
Characteristics Recombinant 2019-nCoV S1+S2 ECD (S-ECD) Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Val11-Gln1208) of 2019-ncov S1+S2 ECD (S-ECD) (Accession #YP_009724390.1) fused with a 6xHis tag at the C-terminus.
Purity > 97 % by SDS-PAGE
Endotoxin Level < 1.0 EU/μg of the protein by LAL method.
Biological Activity Comment Measured by its binding ability in a functional ELISA. Immobilized Recombinant 2019-nCoV Spike S1+S2 ECD-His at 2μg/mL (100 μL/well) can bind Recombinant Human ACE2 with a linear range of 1.5-115.4 ng/mL.
Protein Name
Background Synonym: cov spike Protein, 2019-nCoV,ncov spike Protein, 2019-nCoV,coronavirus spike Protein, 2019-nCoV,S glycoprotein,COVID-19,S protein,Spike glycoprotein
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates thisinteraction.The S protein plays key parts in the induction of neutralizing-antibody and T-cellresponses, as well as protective immunity.
Gene ID 43740568
UniProt P0DTC2
Restrictions For Research Use only
Format Liquid
Buffer Supplied as a 0.22 μm filtered solution in PBS, pH 7.4.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -80 °C
Storage Comment This product is stable at ≤ 70°C for up to 1 year from the date of receipt. For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature.
Supplier Images
Image no. 1 for SARS-CoV-2 Spike (ECD) (Active) protein (His tag) (ABIN6952734) Recombinant 2019-nCoV S1+S2 ECD (S-ECD) Protein was determined by SDS-PAGE with Cooma...
Image no. 2 for SARS-CoV-2 Spike (ECD) (Active) protein (His tag) (ABIN6952734) Immobilized Recombinant 2019-nCoV Spike S1+S2 ECD-His at 2 μg/mL (100 μL/well) can bi...
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