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CD226 Protein (CD226) (AA 19-247) (mFc-His Tag)

This Recombinant CD226 protein is expressed in HEK-293 Cells.
Catalog No. ABIN6961117

Quick Overview for CD226 Protein (CD226) (AA 19-247) (mFc-His Tag) (ABIN6961117)

Target

See all CD226 Proteins
CD226

Protein Type

Recombinant

Origin

  • 18
  • 5
  • 2
  • 1
  • 1
Human

Source

  • 16
  • 5
  • 3
  • 2
  • 1
HEK-293 Cells

Application

ELISA

Purity

The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
  • Protein Characteristics

    AA 19-247

    Purification tag / Conjugate

    This CD226 protein is labelled with mFc-His Tag.

    Purpose

    Recombinant human DNAM-1 protein with C-terminal mouse Fc and 6xHis tag

    Specificity

    DNAM-1 (Glu19-Asn247) mFc (Pro99-Lys330) 6xHis tag

    Characteristics

    Extracellular Domain Protein

    Purification

    Purified from cell culture supernatant by affinity chromatography
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

    Storage

    -20 °C,-80 °C

    Storage Comment

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    Expiry Date

    12 months
  • Target

    CD226

    Alternative Name

    DNAM-1

    Background

    This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants.

    Molecular Weight

    predicted molecular mass of 53.5 kDa after removal of the signal peptide.

    Gene ID

    10666

    UniProt

    Q15762

    Pathways

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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