CD226 Protein (CD226) (AA 19-247) (mFc-His Tag)
Quick Overview for CD226 Protein (CD226) (AA 19-247) (mFc-His Tag) (ABIN6961117)
Target
See all CD226 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- AA 19-247
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Purification tag / Conjugate
- This CD226 protein is labelled with mFc-His Tag.
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Purpose
- Recombinant human DNAM-1 protein with C-terminal mouse Fc and 6xHis tag
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Specificity
- DNAM-1 (Glu19-Asn247) mFc (Pro99-Lys330) 6xHis tag
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Characteristics
- Extracellular Domain Protein
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Purification
- Purified from cell culture supernatant by affinity chromatography
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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Expiry Date
- 12 months
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- CD226
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Alternative Name
- DNAM-1
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Background
- This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants.
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Molecular Weight
- predicted molecular mass of 53.5 kDa after removal of the signal peptide.
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Gene ID
- 10666
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UniProt
- Q15762
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Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
Target
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