CD84 Protein (CD84) (AA 22-225) (His tag,mFc Tag)

Catalog No. ABIN6961120

This Recombinant CD84 protein is expressed in HEK-293 Cells.

Quick Overview for CD84 Protein (CD84) (AA 22-225) (His tag,mFc Tag) (ABIN6961120)

Target: CD84

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Affinity Measurement (AM), Antibody Drug Assay (ADA), Immunoassay (IA), Screening Assay (ScA)

Purity: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Product Details

Protein Characteristics: AA 22-225

Purification tag / Conjugate: This CD84 protein is labelled with His tag,mFc Tag.

Purpose: Recombinant human SLAMF5 protein with C-terminal mouse Fc and 6xHis tag

Specificity: SLAMF5(Lys22-Gly225) mFc(Pro99-Lys330) 6xHis tag

Characteristics: Extracellular Domain Protein

Purification: Purified from cell culture supernatant by affinity chromatography

Application Details

Application Notes: Extracellular Domain Proteins (ECD) can be used as:

• Immunogens for antibody drug development
• Reagents used for CAR-T positive cell monitoring
• Reagents for antibody screening and functional testing
• Reagents for antibody affinity measurement

Comment:

The protein was produced using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target protein.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please see Certificate of Analysis for specific instructions of reconstitution.

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: CD84

Alternative Name: SLAMF5

Background: CD84,SLAMF5,LY9B,SLAMF5
This gene encodes a membrane glycoprotein that is a member of the signaling lymphocyte activation molecule (SLAM) family. This family forms a subset of the larger CD2 cell-surface receptor Ig superfamily. The encoded protein is a homophilic adhesion molecule that is expressed in numerous immune cells types and is involved in regulating receptor-mediated signaling in those cells. Alternate splicing results in multiple transcript variants.

Molecular Weight: predicted molecular mass of 50.3 kDa after removal of the signal peptide.The apparent molecular mass of SLAMF5-mFc-His is 60-80 kDa due to glycosylation.

Gene ID: 8832

UniProt: Q9UIB8