TNFRSF10B Protein (AA 56-182) (mFc Tag)
Quick Overview for TNFRSF10B Protein (AA 56-182) (mFc Tag) (ABIN6961152)
Target
See all TNFRSF10B ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- AA 56-182
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Purification tag / Conjugate
- This TNFRSF10B protein is labelled with mFc Tag.
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Purpose
- Recombinant human TNFRSF10B protein with C-terminal mouse Fc tag
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Specificity
- TNFRSF10B (Ile56-Glu182) mFc(Pro99-Lys330)
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Characteristics
- Extracellular Domain Protein
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Purification
- Purified from cell culture supernatant by affinity chromatography
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Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 56-182) (Active) protein (Biotin,His-Avi Tag)
TNFRSF10B Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 56-182) (Active) protein (hFc Tag)TNFRSF10B Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 56-182) (Active) protein (His-Avi Tag)TNFRSF10B Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 53-180) (Active) protein (His tag)TNFRSF10B Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 56-180) protein (His-DYKDDDDK-Strep II Tag)TNFRSF10B Origin: Human Host: HEK-293T Cells Recombinant WB, SDS, ELISA, PI
Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 56-210) protein (His-DYKDDDDK-Strep II Tag)TNFRSF10B Origin: Human Host: HEK-293T Cells Recombinant WB, SDS, ELISA, PI
Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 56-182) (Active) protein (Fc Tag)TNFRSF10B Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (Active) protein (His tag,Fc Tag)TNFRSF10B Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) protein (His tag,AVI tag)TNFRSF10B Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (Active) protein (His tag)TNFRSF10B Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
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Application Notes
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Extracellular Domain Proteins (ECD) can be used as:
- Immunogens for antibody drug development
- Reagents used for CAR-T positive cell monitoring
- Reagents for antibody screening and functional testing
- Reagents for antibody affinity measurement
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Comment
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The protein was produced using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target protein.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please see Certificate of Analysis for specific instructions of reconstitution.
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Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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Expiry Date
- 12 months
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- TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))
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Alternative Name
- TNFRSF10B
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Background
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TNFRSF10B,TRAILR2,TRAIL-R2,CD262,DR5,KILLER,TRICK2,ZTNFR9,TRICKB
The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. -
Molecular Weight
- predicted molecular mass of 40.5 kDa after removal of the signal peptide.
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Gene ID
- 8795
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UniProt
- O14763
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Pathways
- p53 Signaling, Apoptosis, Positive Regulation of Endopeptidase Activity
Target
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