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MME Protein (Fc Tag)

This Recombinant MME protein is expressed in HEK-293 Cells.
Catalog No. ABIN6964096

Quick Overview for MME Protein (Fc Tag) (ABIN6964096)

Target

See all MME Proteins
MME (Membrane Metallo-Endopeptidase (MME))

Protein Type

Recombinant

Origin

  • 18
  • 5
  • 4
  • 1
Human

Source

  • 10
  • 8
  • 2
  • 2
  • 2
  • 2
HEK-293 Cells

Purity

The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
  • Purification tag / Conjugate

    This MME protein is labelled with Fc Tag.

    Purpose

    Recombinant Human CD10 protein with N-terminal human Fc

    Specificity

    HFc (Glu99-Ala330) CD10 (Tyr52-Trp750)

    Characteristics

    Extracellular Domain Protein

    Purification

    Purified from cell culture supernatant by affinity chromatography
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

    Storage

    -20 °C,-80 °C

    Storage Comment

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    Expiry Date

    12 months
  • Target

    MME (Membrane Metallo-Endopeptidase (MME))

    Alternative Name

    CD10

    Background

    The protein encoded by this gene is a type II transmembrane glycoprotein and a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). The encoded protein is present on leukemic cells of pre-B phenotype, which represent 85 % of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin.

    Molecular Weight

    predicted molecular mass of 106.1 kDa after removal of the signal peptide.

    Gene ID

    4311

    UniProt

    P08473

    Pathways

    RTK Signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration
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