CD8 alpha Protein (Fc Tag)
Quick Overview for CD8 alpha Protein (Fc Tag) (ABIN6964139)
Target
See all CD8 alpha (CD8A) ProteinsProtein Type
Origin
Source
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Purification tag / Conjugate
- This CD8 alpha protein is labelled with Fc Tag.
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Sequence
- CD8A(Ser22-Asp182)+hFc(Glu99-Ala330)
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Characteristics
- Tagged Protein: C-Human Fc tag
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Purification
- affinity purification
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CD8a Molecule (CD8A) (AA 28-196) protein (His tag)
CD8A Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD8a Molecule (CD8A) (AA 22-182) protein (His-Avi Tag,Biotin)CD8A Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
CD8a Molecule (CD8A) (AA 22-182) (Active) protein (His tag)CD8A Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
CD8a Molecule (CD8A) (AA 22-182) (Active) protein (His tag,AVI tag,Biotin)CD8A Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
CD8a Molecule (CD8A) (AA 22-182) protein (His-IF2DI Tag)CD8A Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
CD8a Molecule (CD8A) (AA 22-131) protein (GST tag)CD8A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
CD8a Molecule (CD8A) (AA 1-235) protein (GST tag)CD8A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
CD8a Molecule (CD8A) (Active) protein (His tag)CD8A Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
CD8a Molecule (CD8A) protein (Fc Tag)CD8A Origin: Rat Host: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute with deionized water
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Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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Preservative
- Without preservative
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Storage
- -80 °C
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Storage Comment
- Store at -80°C for 12 months (Avoid repeated freezing and thawing)
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Expiry Date
- 12 months
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- CD8 alpha (CD8A) (CD8a Molecule (CD8A))
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Alternative Name
- CD8A
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Background
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Synonymes: CD8, Leu2, p32
Description: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. -
Molecular Weight
- 43.23 kDa
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UniProt
- P01732
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Pathways
- TCR Signaling
Target
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