CD8 alpha Protein (AA 28-196) (His tag)
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- Target See all CD8 alpha (CD8A) Proteins
- CD8 alpha (CD8A) (CD8a Molecule (CD8A))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 28-196
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CD8 alpha protein is labelled with His tag.
- Purpose
- Mouse CD8 alpha/CD8A Protein
- Sequence
- Lys28-Tyr196
- Characteristics
- Recombinant Mouse CD8 alpha/CD8A Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Lys28-Tyr196.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
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CD8a Molecule (CD8A) (AA 22-182) protein (His-Avi Tag,Biotin)
CD8A Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
CD8a Molecule (CD8A) (AA 22-182) (Active) protein (His tag)CD8A Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
CD8a Molecule (CD8A) (AA 22-182) (Active) protein (His tag,AVI tag,Biotin)CD8A Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
CD8a Molecule (CD8A) (AA 22-182) protein (His-IF2DI Tag)CD8A Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
CD8a Molecule (CD8A) (AA 22-131) protein (GST tag)CD8A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
CD8a Molecule (CD8A) (AA 1-235) protein (GST tag)CD8A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
CD8a Molecule (CD8A) (Active) protein (His tag)CD8A Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
CD8a Molecule (CD8A) protein (Fc Tag)CD8A Origin: Rat Host: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- CD8 alpha (CD8A) (CD8a Molecule (CD8A))
- Alternative Name
- CD8 alpha (CD8A Products)
- Synonyms
- cd8 Protein, LOC100136450 Protein, BB154331 Protein, Ly-2 Protein, Ly-35 Protein, Ly-B Protein, Lyt-2 Protein, zgc:136643 Protein, CD8 Protein, Leu2 Protein, MAL Protein, p32 Protein, RHACD8-4 Protein, CD8a molecule Protein, uncharacterized LOC100125537 Protein, CD8 alpha Protein, CD8 antigen, alpha chain Protein, T-cell surface glycoprotein CD8 alpha chain Protein, Cd8a Protein, LOC100125537 Protein, LOC100136450 Protein, CD8A Protein, cd8a Protein, LOC100126556 Protein
- Background
- CD8 alpha enhances the responses of antigen-specific CTL activated through TCR through binding MHC class I, favoring lipid raft partitioning of TCR, and inducing intracellular signaling. CD8 alpha is also found on dendritic cells and rat macrophages, but whether CD8 alpha enhances responses of a partner receptor, like TCR, to activate these cells is not known.
- Molecular Weight
- 20 kDa. Due to glycosylation, the protein migrates to 32-42 kDa based on Tris-Bis PAGE result.
- Pathways
- TCR Signaling
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