IFNAR1 Protein (AA 28-436) (His tag)
Quick Overview for IFNAR1 Protein (AA 28-436) (His tag) (ABIN6964273)
Target
See all IFNAR1 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- AA 28-436
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Purification tag / Conjugate
- This IFNAR1 protein is labelled with His tag.
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Purpose
- Recombinant Human IFNAR1 Protein with C-terminal 6xHis tag
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Specificity
- IFNAR1(Lys28-Lys436) 6xHis Tag
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Characteristics
- Extracellular Domain Protein
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Purification
- Purified from cell culture supernatant by affinity chromatography
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Interferon alpha/beta Receptor 1 (IFNAR1) (AA 28-436) protein (Fc Tag)
IFNAR1 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Interferon alpha/beta Receptor 1 (IFNAR1) (AA 28-436) protein (mFc Tag)IFNAR1 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Interferon alpha/beta Receptor 1 (IFNAR1) (AA 28-127) protein (GST tag)IFNAR1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Interferon alpha/beta Receptor 1 (IFNAR1) (AA 1-557) protein (GST tag)IFNAR1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Interferon alpha/beta Receptor 1 (IFNAR1) protein (His tag)IFNAR1 Origin: Rhesus Monkey Host: Human Cells Recombinant > 90 % as determined by reducing SDS-PAGE.
Interferon alpha/beta Receptor 1 (IFNAR1) (Active) protein (His tag)IFNAR1 Origin: Mouse Host: HEK-293 Cells Recombinant > 96 % as determined by SDS-PAGE Active
Interferon alpha/beta Receptor 1 (IFNAR1) (AA 27-429) protein (His tag)IFNAR1 Origin: Mouse Host: Baculovirus infected Insect Cells Recombinant > 90 % SDS
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Application Notes
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Extracellular Domain Proteins (ECD) can be used as:
- Immunogens for antibody drug development
- Reagents used for CAR-T positive cell monitoring
- Reagents for antibody screening and functional testing
- Reagents for antibody affinity measurement
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Comment
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The protein was produced using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target protein.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please see Certificate of Analysis for specific instructions of reconstitution.
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Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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Expiry Date
- 12 months
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- IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))
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Alternative Name
- IFNAR1
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Background
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AVP,IFN-alpha-REC,IFNAR,IFNBR,IFRC
The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The protein belongs to the type II cytokine receptor family and functions as an antiviral factor. [provided by RefSeq, Jul 2020] -
Molecular Weight
- predicted molecular mass of 48.0 kDa after removal of the signal peptide.The apparent molecular mass of IFNAR1-His is 70-100 kDa due to glycosylation.
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UniProt
- P17181
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Pathways
- JAK-STAT Signaling, Hepatitis C
Target
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