ROR1 Protein (AA 30-403) (His tag,FITC)
Quick Overview for ROR1 Protein (AA 30-403) (His tag,FITC) (ABIN6973212)
Target
See all ROR1 ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 30-403
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Purification tag / Conjugate
- This ROR1 protein is labelled with His tag,FITC.
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Characteristics
- FITC-Labeled Human ROR1 Protein, His Tag
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Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
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Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1) (AA 30-403) (Active) protein (His-Avi Tag)
ROR1 Origin: Human, Cynomolgus, Rhesus Monkey Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1) (AA 30-403) (Active) protein (hFc Tag)ROR1 Origin: Human, Cynomolgus, Rhesus Monkey Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1) (AA 39-151) (Active) protein (His tag)ROR1 Origin: Human, Cynomolgus, Rhesus Monkey Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1) (AA 30-305) (Active) protein (His tag)ROR1 Origin: Human, Cynomolgus, Rhesus Monkey Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1) (AA 30-403) protein (His tag)ROR1 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1) (AA 30-403) (Active) protein (Biotin,His-Avi Tag)ROR1 Origin: Human, Cynomolgus, Rhesus Monkey Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1) (AA 30-406) (Active) protein (His tag)ROR1 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1) (AA 22-477) (Active) protein (His tag)ROR1 Origin: Dog Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1) (AA 165-305) (Active) protein (His tag)ROR1 Origin: Human, Cynomolgus, Rhesus Monkey Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1) (AA 308-395) (Active) protein (His tag)ROR1 Origin: Human, Cynomolgus, Rhesus Monkey Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Storage
- -20 °C
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- ROR1 (Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1))
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Alternative Name
- ROR1
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Background
- Tyrosine-protein kinase transmembrane receptor ROR1 is also known as Neurotrophic tyrosine kinase, receptor-related 1 (NTRKR1), which belongs to the protein kinase superfamily or tyr protein kinase family or ROR subfamily. ROR1 contains 1 FZ (frizzled) domain, 1 Ig-like C2-type (immunoglobulin-like) domain, 1 kringle domain, 1 protein kinase domain. ROR1 is expressed at high levels during early embryonic development. The expression levels drop strongly around day 16 and there are only very low levels in adult tissues. Isoform Short is strongly expressed in fetal and adult CNS and in a variety of human cancers, including those originating from CNS or PNS neuroectoderm. ROR1 could interact with casein kinase 1 epsilon (CK1ε) to activate phosphoinositide 3-kinase-mediated AKT phosphorylation and cAMP-response-element-binding protein (CREB), which was associated with enhanced tumor-cell growth.
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Molecular Weight
- 43.9 kDa
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Pathways
- RTK Signaling, WNT Signaling, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
Target
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