NOTCH3 Protein (AA 40-467) (Fc Tag)
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- Target See all NOTCH3 Proteins
- NOTCH3 (Notch 3 (NOTCH3))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 40-467
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This NOTCH3 protein is labelled with Fc Tag.
- Purpose
- Human NOTCH3 Protein, Fc Tag
- Purity
- >95 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product NOTCH3 Protein
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Notch 3 (NOTCH3) (AA 1378-1640) protein (His tag)
NOTCH3 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Notch 3 (NOTCH3) (AA 40-467) protein (Fc Tag)NOTCH3 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Notch 3 (NOTCH3) (AA 40-467) protein (His-Avi Tag)NOTCH3 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Notch 3 (NOTCH3) (AA 47-156) protein (GST tag)NOTCH3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5
- Storage
- -20 °C
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- Target
- NOTCH3 (Notch 3 (NOTCH3))
- Alternative Name
- NOTCH3 (NOTCH3 Products)
- Background
- Notch3 is one of four mammalian Notch proteins, which act as signalling receptors and involve in developmental patterning, cell fate decisions, regulation of cell survival and proliferation. Notch3 could interact with membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Via ligand activation, notch intracellular domain (NICD) is released and forms a transcriptional activator RBPJ/RBPSUH complex, which activates genes of the enhancer of split locus. Consequently, the activation of Notch3 can lead to the implementation of differentiation, proliferation and apoptotic programs
- Molecular Weight
- 71.4 kDa
- NCBI Accession
- NP_000426
- Pathways
- Notch Signaling
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