CD39 Protein (AA 38-478) (His tag)
-
- Target See all CD39 (ENTPD1) Proteins
- CD39 (ENTPD1) (Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 38-478
-
Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CD39 protein is labelled with His tag.
- Characteristics
- Human CD39 / ENTPD1 Protein, His Tag (active enzyme)
- Purity
- >95 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product ENTPD1 Protein
-
Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) (AA 38-478) protein (His tag)
ENTPD1 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) (AA 70-197) protein (His-IF2DI Tag)ENTPD1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) (AA 1-510) protein (GST tag)ENTPD1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) (Active) protein (His tag)ENTPD1 Origin: Mouse Host: Baculovirus infected Insect Cells Recombinant > 95 % as determined by SDS-PAGE Active
Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) (AA 1-510) protein (Strep Tag)Crystallography grade ENTPD1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) (AA 1-510) protein (Strep Tag)Crystallography grade ENTPD1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) (AA 38-478) protein (His tag)Crystallography grade ENTPD1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) (AA 38-478) protein (His tag)Crystallography grade ENTPD1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1) (AA 38-478) (Active) protein (mFc Tag)ENTPD1 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Buffer
- Tris and NaCl, pH 8.0
- Storage
- -20 °C
-
- Target
- CD39 (ENTPD1) (Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1))
- Alternative Name
- CD39 (ENTPD1 Products)
- Synonyms
- ATPDase Protein, CD39 Protein, NTPDase-1 Protein, MGC80631 Protein, zgc:100819 Protein, entpd1 Protein, MGC79567 Protein, 2610206B08Rik Protein, AA408691 Protein, Cd39 Protein, ectonucleoside triphosphate diphosphohydrolase 1 Protein, ectonucleoside triphosphate diphosphohydrolase 1 L homeolog Protein, ENTPD1 Protein, Entpd1 Protein, entpd1.L Protein, entpd1 Protein
- Background
- CD39 is also known as Ectonucleoside triphosphate diphosphohydrolase 1, ENTPD1, NTPDase 1, Ecto-ATPDase 1, in the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP. Hydrolyzes ATP and ADP equally well. NTPDase-1 was originally described as CD39, a B lymphocyte cell surface marker, but it is also present on the surface of natural killer cells, T cells, and some endothelial cells.Regulatory T cells(Tregs) mediate immunosuppression through multiple, non-redundant, cell-contact dependent and independent mechanisms, a growing body of evidence suggests an important role for the CD39-CD73-adenosine pathway. CD39 ectonucleotidase is the rate-limiting enzyme of a cascade leading to the generation of suppressive adenosine that alters CD4 and CD8 T cell and natural killer cell antitumor activities.
- Molecular Weight
- 52.3 kDa
- NCBI Accession
- NP_001767
-
