CD39 Protein (His tag)
Quick Overview for CD39 Protein (His tag) (ABIN7320837)
Target
See all CD39 (ENTPD1) ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This CD39 protein is labelled with His tag.
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Purpose
- Recombinant Mouse CD39/ENTPD1 Protein (His Tag)
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Sequence
- Thr38-Ile478
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Characteristics
- Recombinant Mouse ENTPD1 is produced by our Mammalian expression system and the target gene encoding Thr38-Ile478 is expressed with a 6His tag at the C-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Restrictions
- For Research Use only
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Format
- Frozen, Liquid
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Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM Tris,500 mM NaCl,10 % Glycerol, pH 7.4.
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Storage
- -20 °C
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Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- CD39 (ENTPD1) (Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1))
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Alternative Name
- CD39/ENTPD1
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Background
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Background: Ectonucleoside triphosphate diphosphohydrolase-1(NTPDase-1)is an integral membrane protein with an extracellular active site. Recombinant mouse NTPDase-1wasexpressed as a protein lacking its N- andC-terminaltransmembrane domains, resulting in the secretion of the soluble ectodomain. NTPDase-1was originally describedas CD39, a B lymphocyte cell surface marker. but it is also present on the surface of natural killer cells, T cells, and some endothelial cells. NTPDase1hydrolyzes the β-andγ phosphate residues of nucleotides, preferring ATP as the substrate. Through its hydrolysis of extracellular nucleotides, NTPDase-1plays arole in the regulation of purinergic signaling. NTPDase-1is involved in the processes of thromboregulation and vascular inflammation. The administration ofsoluble NTPDase-1may have therapeutic applications for the treatment of some vascular and transplantation-associateddiseases.
Synonym: Ectonucleoside triphosphate diphosphohydrolase 1, NTPDase 1, NTPDase 1, Ecto-ATP diphosphohydrolase 1, Ecto-ATPDase 1, Ecto-ATPase 1, Ecto-apyrase, Lymphoid cell activation antigen, CD39
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Molecular Weight
- 50.5 kDa
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UniProt
- P55772
Target
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