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PVRL4 Protein (AA 32-349) (Fc Tag)

Recombinant PVRL4 protein expressed in HEK-293 Cells.
Catalog No. ABIN7013402

Quick Overview for PVRL4 Protein (AA 32-349) (Fc Tag) (ABIN7013402)

Target

See all PVRL4 Proteins
PVRL4 (Poliovirus Receptor-Related 4 (PVRL4))

Protein Type

Recombinant

Biological Activity

Active

Origin

  • 28
  • 6
  • 2
  • 1
  • 1
  • 1
Human

Source

  • 23
  • 6
  • 4
  • 3
  • 2
  • 1
HEK-293 Cells

Purity

>95 % as determined by SDS-PAGE.
  • Protein Characteristics

    AA 32-349

    Purification tag / Conjugate

    This PVRL4 protein is labelled with Fc Tag.

    Sequence

    AA 32-349

    Endotoxin Level

    Less than 0.1 EU per μg by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    Tris with Glycine, Arginine and NaCl,  pH 7.5

    Handling Advice

    Please avoid repeated freeze-thaw cycles.

    Storage

    -20 °C
  • Target

    PVRL4 (Poliovirus Receptor-Related 4 (PVRL4))

    Alternative Name

    Nectin-4

    Background

    Nectin-4 (gene name PVRL4, poliovirus receptor-like 4) is a 66 kDa type I transmembrane glycoprotein belonging to the Nectin family of Ig superfamily proteins. Nectins are cell adhesion molecules that play a key role in various biological processes such as polarity, proliferation, differentiation and migration, for epithelial, endothelial, immune and neuronal cells, during development and adult life. Nectin-4 is a tumor-associated antigen in 50 % , 49 % and 86 %o of breast, ovarian and lung carcinomas, respectively, mostly on tumors of bad prognosis. Its expression is not detected in the corresponding normal tissues.

    Molecular Weight

    60.5 kDa

    NCBI Accession

    NP_112178

    Pathways

    Cell-Cell Junction Organization
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