Thymic Stromal Lymphopoietin Protein (TSLP) (AA 29-159) (His tag)
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- Target See all Thymic Stromal Lymphopoietin (TSLP) Proteins
- Thymic Stromal Lymphopoietin (TSLP)
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 29-159
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Origin
- Cynomolgus
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Thymic Stromal Lymphopoietin protein is labelled with His tag.
- Sequence
- AA 29-159
- Characteristics
- Human Tyk2 Protein, His Tag (MALS verified)
- Purity
- >90 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product TSLP Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Storage
- -20 °C
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- Target
- Thymic Stromal Lymphopoietin (TSLP)
- Alternative Name
- TSLP (TSLP Products)
- Background
- Thymic stromal lymphopoietin (TSLP) is an epithelial cell-derived cytokine involved in the pathology of inflammatory skin diseases, and is widely expressed by epithelial cells. Human TSLP cDNA encodes a 159 amino acid (aa) residue precursor protein with a 28 aa signal sequence (4, 5). Human TSLP has been shown to developing nondeletional central tolerance, amplifying epithelium-induced class switching, inducing atopic diseases and maintaining intestinal noninflammatory environment. Among diverse cells responding to Human TSLP, CD11c+ dendritic cells are the most obviously characterized target cells.
- Molecular Weight
- 11.7 kDa and 5.4 kDa
- NCBI Accession
- XP_005557555
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