Thymic Stromal Lymphopoietin Protein (TSLP) (AA 29-159) (His tag)
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- Target See all Thymic Stromal Lymphopoietin (TSLP) Proteins
- Thymic Stromal Lymphopoietin (TSLP)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 29-159
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Origin
- Cynomolgus
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Thymic Stromal Lymphopoietin protein is labelled with His tag.
- Purpose
- Cynomolgus TSLP Protein
- Sequence
- Tyr29-Gln159
- Characteristics
- Recombinant Cynomolgus TSLP Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Tyr29-Gln159.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Cynomolgus TSLP, His Tag at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Anti-TSLP Antibody, hFc Tag with the EC50 of 7.8ng/ml determined by ELISA. See testing image for detail.
- Top Product
- Discover our top product TSLP Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- Thymic Stromal Lymphopoietin (TSLP)
- Alternative Name
- TSLP (TSLP Products)
- Synonyms
- TSLP Protein, thymic stromal lymphopoietin Protein, TSLP Protein, Tslp Protein
- Background
- Thymic Stromal Lymphopoietin (TSLP) was originally identified as an activity from the conditioned medium of a mouse thymic stromal cell line that promoted the development of B cells. Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c dendritic cells. Can induce allergic inflammation by directly activating mast cells.
- Molecular Weight
- 16.3 kDa. Due to glycosylation, the protein migrates to 23-26 kDa based on Tris-Bis PAGE result.
- UniProt
- A0A7N9CAT7
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