MICA Protein (AA 24-308) (Fc Tag)
Quick Overview for MICA Protein (AA 24-308) (Fc Tag) (ABIN7013491)
Target
See all MICA ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 24-308
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Purification tag / Conjugate
- This MICA protein is labelled with Fc Tag.
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Characteristics
- Human MICA Protein, Fc Tag (MALS verified)
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Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
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Application Notes
- MALS verified
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Storage
- -20 °C
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- MICA (MHC Class I Polypeptide-Related Sequence A (MICA))
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Alternative Name
- MICA
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Background
- MHC class I polypeptide-related sequence A (MICA) belongs to the MHC class I family and MIC subfamily. MICA contains one Ig-like C1-type (immunoglobulin-like) domain. Unlike classical MHC class I molecules, MICA does not form a heterodimer with beta-2-microglobulin. MICA acts as a stress-induced self-antigen that is recognized by gamma delta T-cells. MICA is ligand for the KLRK1/NKG2D receptor. MICA bind to KLRK1 leads to cell lysis.
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Molecular Weight
- 59.3 kDa
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Pathways
- Activation of Innate immune Response, Transition Metal Ion Homeostasis, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
Target
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