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RNF43 Protein (AA 44-197) (Fc Tag)

This Recombinant RNF43 protein is expressed in HEK-293 Cells.
Catalog No. ABIN7013543
$495.08
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Quick Overview for RNF43 Protein (AA 44-197) (Fc Tag) (ABIN7013543)

Target

See all RNF43 Proteins
RNF43 (Ring Finger Protein 43 (RNF43))

Protein Type

Recombinant

Biological Activity

Active

Origin

  • 4
  • 2
Human

Source

  • 4
  • 1
  • 1
HEK-293 Cells

Purity

>95 % as determined by SDS-PAGE.
  • Protein Characteristics

    AA 44-197

    Purification tag / Conjugate

    This RNF43 protein is labelled with Fc Tag.

    Characteristics

    Human RNF43 Protein, Fc Tag (MALS verified)

    Endotoxin Level

    Less than 1.0 EU per μg by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    PBS, pH 7.4

    Storage

    -20 °C
  • Target

    RNF43 (Ring Finger Protein 43 (RNF43))

    Alternative Name

    RNF43

    Background

    E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination, endocytosis and subsequent degradation of Wnt receptor complex components Frizzled. Acts on both canonical and non-canonical Wnt signaling pathway. Along with RSPO2 and ZNRF3, constitutes a master switch that governs limb specification (By similarity)

    Molecular Weight

    43.5 kDa

    Pathways

    WNT Signaling
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