RNF43 Protein (AA 44-197) (Fc Tag)
Quick Overview for RNF43 Protein (AA 44-197) (Fc Tag) (ABIN7013543)
Target
See all RNF43 ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 44-197
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Purification tag / Conjugate
- This RNF43 protein is labelled with Fc Tag.
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Characteristics
- Human RNF43 Protein, Fc Tag (MALS verified)
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Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Storage
- -20 °C
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- RNF43 (Ring Finger Protein 43 (RNF43))
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Alternative Name
- RNF43
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Background
- E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination, endocytosis and subsequent degradation of Wnt receptor complex components Frizzled. Acts on both canonical and non-canonical Wnt signaling pathway. Along with RSPO2 and ZNRF3, constitutes a master switch that governs limb specification (By similarity)
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Molecular Weight
- 43.5 kDa
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Pathways
- WNT Signaling
Target
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