SARS-CoV-2 Nucleocapsid Protein (SARS-CoV-2 N) (B.1.1.529 - Omicron) (His tag)
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- Target See all SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N) Proteins
- SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N)
- Protein Type
- Recombinant
- Protein Characteristics
- B.1.1.529 - Omicron
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Origin
- SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Omicron
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This SARS-CoV-2 Nucleocapsid protein is labelled with His tag.
- Application
- SDS-PAGE (SDS), ELISA
- Purpose
- SARS-CoV-2 Nucleocapsid protein, His Tag (B.1.1.529/Omicron)
- Characteristics
- SARS-CoV-2 Nucleocapsid protein, His Tag (B.1.1.529/Omicron) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Ala 419 (Accession # QHO62115.1(P13L, ERS31-33del, R203K, G204R). The mutations are identified on the SARS-CoV-2 Omicron variant (Pango lineage: B.1.1.529; GISAID clade: GR/484A; Nextstrain clade: 21K). Predicted N-terminus: Met 1
- Purity
- > 95% as determined by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product SARS-CoV-2 N Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C/-80 °C
- Storage Comment
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For long term storage, the product should be stored at lyophilized state at -20°C or lower.This product is stable after storage at:
4-8°C for 12 months in lyophilized state,
-70°C for 3 months under sterile conditions after reconstitution. - Expiry Date
- 12 monts
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- Target
- SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N)
- Alternative Name
- SARS-CoV-2 N protein (SARS-CoV-2 N Products)
- Synonyms
- nucleocapsid phosphoprotein Protein, N Protein
- Target Type
- Viral Protein
- Background
- Nucleocapsid (N) protein is the most abundant protein found in coronavirus. CoV N protein is a highly immunogenic phosphoprotein important for viral genome replication and modulation of cell signaling pathways. It was first identified by a research team while they were screening for ADP-ribosylated proteins during coronavirus (CoV) infection (Grunewald M. E., et al. 2017, Virology; 517: 62-68). The array of diverse functional activities accommodated in N protein makes it more than a structural protein but also an interesting target in the development of antiviral therapeutics. Because of the conservation of N protein sequence and its strong immunogenicity, N protein of coronavirus is chosen as a diagnostic tool.
- Molecular Weight
- 47.3 kDa
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