PTK7 Protein (AA 31-704) (Fc Tag)

Catalog No. ABIN7092672

Recombinant PTK7 protein expressed in HEK-293 Cells.

Quick Overview for PTK7 Protein (AA 31-704) (Fc Tag) (ABIN7092672)

Target: PTK7 (PTK7 Protein tyrosine Kinase 7 (PTK7))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Affinity Measurement (AM), Antibody Drug Assay (ADA), Immunoassay (IA), Screening Assay (ScA)

Purity: The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining.

Product Details

Protein Characteristics: AA 31-704

Purification tag / Conjugate: This PTK7 protein is labelled with Fc Tag.

Purpose: Recombinant Human PTK7 protein with C-terminal human Fc

Specificity: PTK7(Ala31-Thr704) hFc(Glu99-Ala330)

Characteristics: Extracellular Domain Protein

Purification: Purified from cell culture supernatant by affinity chromatography

Application Details

Application Notes: Extracellular Domain Proteins (ECD) can be used as:

• Immunogens for antibody drug development
• Reagents used for CAR-T positive cell monitoring
• Reagents for antibody screening and functional testing
• Reagents for antibody affinity measurement

Comment:

The protein was produced using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target protein.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please see Certificate of Analysis for specific instructions of reconstitution.

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: PTK7 (PTK7 Protein tyrosine Kinase 7 (PTK7))

Alternative Name: PTK7

Background: CCK-4,CCK4
This gene encodes a member of the receptor protein tyrosine kinase family of proteins that transduce extracellular signals across the cell membrane. The encoded protein lacks detectable catalytic tyrosine kinase activity, is involved in the Wnt signaling pathway and plays a role in multiple cellular processes including polarity and adhesion. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Molecular Weight: predicted molecular mass of 100.8 kDa after removal of the signal peptide.The apparent molecular mass of PTK7-hFc is 100-130 kDa due to glycosylation.

Gene ID: 5754

UniProt: Q13308

Pathways: RTK Signaling, Tube Formation