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FAP Protein (AA 30-760) (His tag)

FAP Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Catalog No. ABIN7092782
  • Target See all FAP Proteins
    FAP (Fibroblast Activation Protein, alpha (FAP))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 30-760
    Origin
    • 19
    • 8
    • 3
    • 3
    Human
    Source
    • 19
    • 7
    • 2
    • 2
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This FAP protein is labelled with His tag.
    Purpose
    Recombinant human FAP(30-760) protein with N-terminal 6xHis tag
    Specificity
    6xHis tag FAP (30-760) (Arg30-Asp760)
    Characteristics
    Extracellular Domain Protein
    Purification
    Purified from cell culture supernatant by affinity chromatography
    Purity
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product FAP Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    FAP (Fibroblast Activation Protein, alpha (FAP))
    Alternative Name
    FAP (FAP Products)
    Background
    The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    Molecular Weight
    predicted molecular mass of 85.4 kDa after removal of the signal peptide. The apparent molecular mass of His-FAP(30-760) is 100-130 kDa due to glycosylation.
    UniProt
    Q12884
    Pathways
    Tube Formation
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