FAP Protein (AA 30-760) (His tag)
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- Target See all FAP Proteins
- FAP (Fibroblast Activation Protein, alpha (FAP))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 30-760
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This FAP protein is labelled with His tag.
- Purpose
- Recombinant human FAP(30-760) protein with N-terminal 6xHis tag
- Specificity
- 6xHis tag FAP (30-760) (Arg30-Asp760)
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product FAP Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- FAP (Fibroblast Activation Protein, alpha (FAP))
- Alternative Name
- FAP (FAP Products)
- Background
- The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
- predicted molecular mass of 85.4 kDa after removal of the signal peptide. The apparent molecular mass of His-FAP(30-760) is 100-130 kDa due to glycosylation.
- UniProt
- Q12884
- Pathways
- Tube Formation
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