FAP Protein (AA 26-760) (His-Avi Tag,Biotin)
-
- Target See all FAP Proteins
- FAP (Fibroblast Activation Protein, alpha (FAP))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 26-760
-
Origin
- Cynomolgus
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This FAP protein is labelled with His-Avi Tag,Biotin.
- Purpose
- Biotinylated Cynomolgus FAP Protein
- Sequence
- Leu26-Asp760
- Characteristics
- Recombinant Biotinylated Cynomolgus FAP Protein is expressed from HEK293 with His tag and Avi tag at the N-Terminus.It contains Leu26-Asp760.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Anti-FAP Antibody, hFc Tag at 5μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Cynomolgus FAP, His Tag with the EC50 of 58.5ng/ml determined by ELISA. See testing image for detail.
- Top Product
- Discover our top product FAP Protein
-
-
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- Supplied as 0.22μm filtered solution in 20 mM Tris, 500 mM NaCl, 200 mM Arginine ( pH 8.2).
- Storage
- -80 °C
- Storage Comment
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
-
- Target
- FAP (Fibroblast Activation Protein, alpha (FAP))
- Alternative Name
- FAP (FAP Products)
- Synonyms
- fap-A Protein, gene 13 Protein, FAP Protein, fapa Protein, dppiv Protein, seprase Protein, DPPIV Protein, FAPA Protein, fibroblast activation protein Protein, fibroblast activation protein alpha L homeolog Protein, fibroblast activation protein alpha Protein, fibroblast activation protein, alpha Protein, prolyl endopeptidase FAP Protein, Fap Protein, fap.L Protein, FAP Protein, fap Protein, LOC100547273 Protein
- Background
- Fibroblast activation protein (FAP) is a serine protease that has been reported in fibroblasts and some carcinoma cells, which correlates with poor patient outcomes. FAP can be induced under hypoxia which is also vital in the malignant behaviors of cancer cells.
- Molecular Weight
- 88 kDa. Due to glycosylation, the protein migrates to 90-110 kDa based on Tris-Bis PAGE result.
- NCBI Accession
- XP_005573377
- Pathways
- Tube Formation
-