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FAP Protein (AA 26-760) (His-Avi Tag,Biotin)

FAP Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7274582
  • Target See all FAP Proteins
    FAP (Fibroblast Activation Protein, alpha (FAP))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 26-760
    Origin
    • 18
    • 10
    • 3
    • 2
    Cynomolgus
    Source
    • 17
    • 6
    • 4
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This FAP protein is labelled with His-Avi Tag,Biotin.
    Purpose
    Biotinylated Cynomolgus FAP Protein
    Sequence
    Leu26-Asp760
    Characteristics
    Recombinant Biotinylated Cynomolgus FAP Protein is expressed from HEK293 with His tag and Avi tag at the N-Terminus.It contains Leu26-Asp760.
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Anti-FAP Antibody, hFc Tag at 5μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Cynomolgus FAP, His Tag with the EC50 of 58.5ng/ml determined by ELISA. See testing image for detail.
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    Discover our top product FAP Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Supplied as 0.22μm filtered solution in 20 mM Tris, 500 mM NaCl, 200 mM Arginine ( pH 8.2).
    Storage
    -80 °C
    Storage Comment
    Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    FAP (Fibroblast Activation Protein, alpha (FAP))
    Alternative Name
    FAP (FAP Products)
    Synonyms
    fap-A Protein, gene 13 Protein, FAP Protein, fapa Protein, dppiv Protein, seprase Protein, DPPIV Protein, FAPA Protein, fibroblast activation protein Protein, fibroblast activation protein alpha L homeolog Protein, fibroblast activation protein alpha Protein, fibroblast activation protein, alpha Protein, prolyl endopeptidase FAP Protein, Fap Protein, fap.L Protein, FAP Protein, fap Protein, LOC100547273 Protein
    Background
    Fibroblast activation protein (FAP) is a serine protease that has been reported in fibroblasts and some carcinoma cells, which correlates with poor patient outcomes. FAP can be induced under hypoxia which is also vital in the malignant behaviors of cancer cells.
    Molecular Weight
    88 kDa. Due to glycosylation, the protein migrates to 90-110 kDa based on Tris-Bis PAGE result.
    NCBI Accession
    XP_005573377
    Pathways
    Tube Formation
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