BST1 Protein (AA 29-292) (Fc Tag)

Catalog No. ABIN7092796

This Recombinant BST1 protein is produced in HEK-293 Cells.

Quick Overview for BST1 Protein (AA 29-292) (Fc Tag) (ABIN7092796)

Target: BST1 (Bone Marrow Stromal Cell Antigen 1 (BST1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Screening Assay (ScA), Affinity Measurement (AM), Antibody Drug Assay (ADA), Immunoassay (IA)

Purity: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Product Details

Protein Characteristics: AA 29-292

Purification tag / Conjugate: This BST1 protein is labelled with Fc Tag.

Purpose: Recombinant Human BST1 with C-terminal human Fc tag

Specificity: BST1(Gly29-Lys292) hFc(Glu99-Ala330)

Characteristics: Extracellular Domain Protein

Purification: Purified from cell culture supernatant by affinity chromatography

Application Details

Application Notes: Extracellular Domain Proteins (ECD) can be used as:

• Immunogens for antibody drug development
• Reagents used for CAR-T positive cell monitoring
• Reagents for antibody screening and functional testing
• Reagents for antibody affinity measurement

Comment:

The protein was produced using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target protein.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please see Certificate of Analysis for specific instructions of reconstitution.

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: BST1 (Bone Marrow Stromal Cell Antigen 1 (BST1))

Alternative Name: BST1

Background: CD157
Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33 % similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population. [provided by RefSeq, Jul 2008]

Molecular Weight: predicted molecular mass of 56.1 kDa after removal of the signal peptide. The apparent molecular mass of BST1-hFc is 55-70 kDa due to glycosylation.

UniProt: Q10588