TENM4 Protein (AA 367-2771) (His tag)

Catalog No. ABIN7092866

This Recombinant TENM4 protein is expressed in HEK-293 Cells.

Quick Overview for TENM4 Protein (AA 367-2771) (His tag) (ABIN7092866)

Target: TENM4 (Teneurin Transmembrane Protein 4 (TENM4))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Application: Affinity Measurement (AM), Antibody Drug Assay (ADA), Immunoassay (IA), Screening Assay (ScA)

Purity: The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.

Product Details

Protein Characteristics: AA 367-2771

Purification tag / Conjugate: This TENM4 protein is labelled with His tag.

Purpose: Recombinant mouse TENM4 protein with N-terminal 6xHis tag

Specificity: 6xHis tag Mouse TENM4(Gly367-Arg2771)

Characteristics: Extracellular Domain Protein

Purification: Purified from cell culture supernatant by affinity chromatography

Application Details

Application Notes: Extracellular Domain Proteins (ECD) can be used as:

• Immunogens for antibody drug development
• Reagents used for CAR-T positive cell monitoring
• Reagents for antibody screening and functional testing
• Reagents for antibody affinity measurement

Comment:

The protein was produced using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target protein.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please see Certificate of Analysis for specific instructions of reconstitution.

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: TENM4 (Teneurin Transmembrane Protein 4 (TENM4))

Alternative Name: TENM4

Background: Doc4,ELM2,l(7)-3Rn,l7Rn3,mKIAA1302,Odz4,R75022,Ten-m4
Involved in neural development, regulating the establishment of proper connectivity within the nervous system. Plays a role in the establishment of the anterior-posterior axis during gastrulation. Regulates the differentiation and cellular process formation of oligodendrocytes and myelination of small-diameter axons in the central nervous system (CNS). Promotes activation of focal adhesion kinase. May function as a cellular signal transducer.[UniProtKB/Swiss-Prot Function]

Molecular Weight: predicted molecular mass of 269.0 kDa after removal of the signal peptide.

UniProt: Q3UHK6