Caspase 8 Protein (CASP8) (AA 217-374) (His tag)

Catalog No. ABIN7122169

Recombinant Caspase 8 protein expressed in Escherichia coli (E. coli).

Quick Overview for Caspase 8 Protein (CASP8) (AA 217-374) (His tag) (ABIN7122169)

Target: Caspase 8 (CASP8)

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: Western Blotting (WB), ELISA

Purity: Greater than 90 % as determined by SDS-PAGE.

Product Details

Protein Characteristics: AA 217-374

Purification tag / Conjugate: This Caspase 8 protein is labelled with His tag.

Purpose: Recombinant Human Casp8

Sterility: 0.2 μm filtered

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Centrifuge the vial before opening, reconstitute in sterile distilled water to a concentration of 0.1-1 mg/mL by gently pipetting 2-3 times, don't vortex.

Buffer: Lyophilized from a 0.2 μm filtered solution in 10 mM Hepes, 500 mM NaCl with 5 % trehalose, pH 7.4.

Storage: -20 °C,-80 °C

Storage Comment: The lyophilized protein is stable at -20 °C for up to 1 year. After reconstitution, the protein solution is stable at -20 to -80 °C for 3 months or 1 week at 2 to 8 °C under sterile conditions. For extended storage, it is recommended to further dilute in working aliquots, avoid repeated freeze/thaw cycle.

Expiry Date: 12 months

Target Details

Target: Caspase 8 (CASP8)

Alternative Name: Casp8

Background: ALPS2B, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein, Apoptosis related cysteine peptidase, Apoptotic cysteine protease, Apoptotic protease Mch-5, Apoptotic protease Mch5, CAP 4, CAP4, CASP-8, CASP8, CASP8_HUMAN, Caspase 8

Molecular Weight: 17.9 kDa

UniProt: Q14790

Pathways: Apoptosis, Caspase Cascade in Apoptosis, TLR Signaling, Activation of Innate immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades