CD74 Protein (AA 73-232) (His tag)

Catalog No. ABIN7123354

Recombinant CD74 protein expressed in Escherichia coli (E. coli).

Quick Overview for CD74 Protein (AA 73-232) (His tag) (ABIN7123354)

Target: CD74 (HLA-DR-gamma (CD74))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: Western Blotting (WB), ELISA

Purity: Greater than 90 % as determined by SDS-PAGE.

Product Details

Protein Characteristics: AA 73-232

Purification tag / Conjugate: This CD74 protein is labelled with His tag.

Purpose: Recombinant Human CD74

Sterility: 0.2 μm filtered

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Centrifuge the vial before opening, reconstitute in sterile distilled water to a concentration of 0.1-1 mg/mL by gently pipetting 2-3 times, don't vortex.

Buffer: Lyophilized from a 0.2 μm filtered solution in 10 mM Hepes, 500 mM NaCl with 5 % trehalose, pH 7.4.

Storage: -20 °C,-80 °C

Storage Comment: The lyophilized protein is stable at -20 °C for up to 1 year. After reconstitution, the protein solution is stable at -20 to -80 °C for 3 months or 1 week at 2 to 8 °C under sterile conditions. For extended storage, it is recommended to further dilute in working aliquots, avoid repeated freeze/thaw cycle.

Expiry Date: 12 months

Target Details

Target: CD74 (HLA-DR-gamma (CD74))

Alternative Name: CD74

Background: CD 74, CD74, CD74 antigen, CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated), CD74 Molecule, CD74 Molecule, major histocompatibility complex, class II invariant chain, CLIP, DHLAG, Gamma chain of class II antigens

Molecular Weight: 17.5 kDa

UniProt: P04233

Pathways: Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Negative Regulation of intrinsic apoptotic Signaling, Cancer Immune Checkpoints