Quick Overview for CD74 Protein (His tag,mFc Tag) (ABIN7320543)
Target
See all CD74 ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This CD74 protein is labelled with His tag,mFc Tag.
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Purpose
- Recombinant Mouse CD74 Protein (mFc & His Tag)
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Sequence
- Gln56-Leu215
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Characteristics
- Recombinant Mouse HLA class II histocompatibility antigen gamma chain is produced by our Mammalian expression system and the target gene encoding Gln56-Leu215 is expressed with a mFc, 6His tag at the C-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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HLA-DR-gamma (CD74) (AA 1-296) protein (His tag)
custom-made CD74 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
HLA-DR-gamma (CD74) (AA 1-279) protein (His tag)custom-made CD74 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
HLA-DR-gamma (CD74) (AA 56-279) (Active) protein (His tag)CD74 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
HLA-DR-gamma (CD74) (AA 1-160) protein (GST tag)CD74 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
HLA-DR-gamma (CD74) protein (His tag)CD74 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
HLA-DR-gamma (CD74) (AA 73-232) protein (His tag)CD74 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
HLA-DR-gamma (CD74) (AA 99-330) protein (Fc Tag)CD74 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- CD74 (HLA-DR-gamma (CD74))
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Alternative Name
- CD74
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Background
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Background: Mouse HLA class II histocompatibility antigen gamma chain (CD74), is a single-pass type II membrane protein that in humans is encoded by the CD74 gene. It contains 1 thyroglobulin type-1 domain. CD74 Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place.
Synonym: Cluster of Differentiation 74,CD74 antigen, CD74 Molecule, major histocompatibility complex, class II invariant chain, DHLAG gamma chain of class II antigens, HLA class II histocompatibility antigen gamma chain, HLADG, HLA-DR antigens-associated invariant chain, HLA-DR-gamma, Ia antigen-associated invariant chain, Ia-associated invariant chain, Ia-GAMMA, MHC HLA-DR gamma chain, CD74, DHLAG, HLADG, Ia-gamma, INVG34,
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Molecular Weight
- 44.5 kDa
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Pathways
- Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Negative Regulation of intrinsic apoptotic Signaling, Cancer Immune Checkpoints
Target
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