IL-6 Receptor Protein (AA 229-468) (His-IF2DI Tag)

Catalog No. ABIN7123612

Recombinant IL-6 Receptor protein expressed in Escherichia coli (E. coli).

Quick Overview for IL-6 Receptor Protein (AA 229-468) (His-IF2DI Tag) (ABIN7123612)

Target: IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: Western Blotting (WB), ELISA

Purity: Greater than 90 % as determined by SDS-PAGE.

Product Details

Protein Characteristics: AA 229-468

Purification tag / Conjugate: This IL-6 Receptor protein is labelled with His-IF2DI Tag.

Purpose: Recombinant Human IL-6R

Sterility: 0.2 μm filtered

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Centrifuge the vial before opening, reconstitute in sterile distilled water to a concentration of 0.1-1 mg/mL by gently pipetting 2-3 times, don't vortex.

Buffer: Lyophilized from a 0.2 μm filtered solution in 10 mM Hepes, 500 mM NaCl with 5 % trehalose, pH 7.4.

Storage: -20 °C,-80 °C

Storage Comment: The lyophilized protein is stable at -20 °C for up to 1 year. After reconstitution, the protein solution is stable at -20 to -80 °C for 3 months or 1 week at 2 to 8 °C under sterile conditions. For extended storage, it is recommended to further dilute in working aliquots, avoid repeated freeze/thaw cycle.

Expiry Date: 12 months

Target Details

Target: IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

Alternative Name: IL-6R

Background: CD 126, CD126, CD126 antigen, gp80, IL 6R, IL 6R 1, IL 6R alpha, IL-6 receptor alpha chain, IL-6 receptor subunit alpha, IL-6R 1, IL-6R subunit alpha, IL-6R-alpha, IL-6RA, IL6Q, Il6r, IL6RA, IL6RA_HUMAN, IL6RQ, Interleukin 6 receptor, interleukin 6 receptor

Molecular Weight: 47.9 kDa

UniProt: P08887

Pathways: JAK-STAT Signaling, Autophagy, Growth Factor Binding, Cancer Immune Checkpoints