CD79b Protein (PE,His tag)

Catalog No. ABIN7125887

Recombinant CD79b protein expressed in HEK-293 Cells.

Quick Overview for CD79b Protein (PE,His tag) (ABIN7125887)

Target: CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Product Details

Purification tag / Conjugate: This CD79b protein is labelled with PE,His tag.

Purpose: PE-Labeled Human CD79B Protein, His Tag (Site-specific conjugation)

Sequence: Ala 29 - Asp 159

Characteristics: PE-Labeled Human CD79B, His Tag is produced via site-specific conjugation of PE to Human CD79B, His Tag under optimal conditions with a proprietary technology. Human CD79B, His Tag is expressed from human 293 cells (HEK293). It contains AA Ala 29 - Asp 159 (Accession # P40259-1).

Application Details

Application Notes: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 18.8 kDa.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: PBS, 0.5 % BSA, pH 7.4

Storage: -20 °C

Storage Comment: -20°C, aviod light

Target Details

Target: CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))

Alternative Name: CD79B

Background: Synonyms: CD79b,B29,IGB,Ig-beta,
B-cell antigen receptor complex-associated protein beta chain (CD79b) is also known as B-cell-specific glycoprotein B29, Ig-beta,Immunoglobulin-associated B29 protein, B29 and IGB, which is a single-pass type I membrane protein containing one Ig-like V-type ( immunoglobulin-like ) domain and one ITAM domain.CD79b is required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR).CD79b can enhance phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation. Defects in CD79b are the cause of agammaglobulinemia type 6 (AGM6) that is a primary immunodeficiency characterized by profoundly low or absent serum antibodies and low or absent circulating B cells due to an early block of B-cell development.

Molecular Weight: 18.8 kDa

NCBI Accession: NP_000617

Pathways: BCR Signaling