IL17C Protein (His tag)
Quick Overview for IL17C Protein (His tag) (ABIN7194048)
Target
See all IL17C ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This IL17C protein is labelled with His tag.
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Purpose
- Mouse IL-17C Protein, His Tag
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Sequence
- Asp 17 - Gln 194
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Characteristics
- Mouse IL-17C, His Tag is expressed from human 293 cells (HEK293). It contains AA Asp 17 - Gln 194 (Accession # Q8K4C5-1).
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Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
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Interleukin 17C (IL17C) (AA 19-197) protein (His-Avi Tag)
IL17C Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by SEC-HPLC
Interleukin 17C (IL17C) (AA 19-197) protein (Fc Tag)IL17C Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Interleukin 17C (IL17C) (AA 1-197) protein (GST tag)IL17C Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Interleukin 17C (IL17C) (AA 19-197) (Active) protein (His tag)IL17C Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Interleukin 17C (IL17C) (AA 19-197) (Active) protein (His tag,AVI tag,Biotin)IL17C Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
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Application Notes
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 21.7 kDa. The protein migrates as 25-27 kDa under reducing (R) condition due to glycosylation.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS, 0.5 M Arginine, pH 7.4
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Storage
- -20 °C
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Storage Comment
- For long term storage, the product should be stored at lyophilized state at -20°C or lower.
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- IL17C (Interleukin 17C (IL17C))
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Alternative Name
- IL-17C
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Background
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Synonyms: IL-17C,Cytokine CX2,IL17C,
Description: Interleukin-17C(IL-17C) is a glycosylated cytokine that plays an important role in mucosal immunity and chronic inflammation. IL-17C binds to IL-17 RE with high affinity and to IL-17 RA with low affinity, binds to a heterodimer formed by IL17RA and IL17RE. Enhanced IL17C/IL17RE signaling may also lead to greater susceptibility to autoimmune diseases. Stimulates the production of antibacterial peptides and proinflammatory molecules for host defense by signaling through the NF-kappa-B and MAPK pathways. Acts synergically with IL22 in inducing the expression of antibacterial peptides, including S100A8, S100A9, REG3A and REG3G. Synergy is also observed with TNF and IL1B in inducing DEFB2 from keratinocytes. -
Molecular Weight
- 21.7 kDa
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NCBI Accession
- NP_665833
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Pathways
- Cellular Response to Molecule of Bacterial Origin
Target
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